Abstract： Objective： To observe the clinical effect of the therapy of Huatan Xiaojie Decoction combined with scraping and prickling method on adenoid hypertrophy in children. Methods： A total of 120 children with adenoidal hypertrophy who were treated in the First Affiliated Hospital of Henan University of Chinese Medicine from January 2021 to December 2023 were selected as the study objects and divided into the western medicine group，the scraping group and the combination group according to the random number table method， with 40 cases in each group. The western medicine group treated with conventional western medicine，the scraping group was additionally given scraping and prickling based on the treatment of the western medicine group，and the combination group was additionally treated with Huatan Xiaojie Decoction based on the treatment of the scraping group. After four weeks of continuous treatment， the clinical effects in the three groups were evaluated；the disappearance time of main symptoms and the incidence of adverse reactions were recorded；the levels of serum inflammatory factors [interleukin-4 （IL-4），interleukin-6 （IL- 6） and tumor necrosis factor-α （TNF-α）] and the degree of adenoid hypertrophy [adenoid-nasopharyngeal ratio （A/N ratio）] were compared before and after treatment among the three groups. Results： The total effective rate in the combination group was 95.00% （38/40），higher than that of 80.00% （32/40） in the scraping group and 72.50% （29/ 40） in the western medicine group，differences being significant （P＜0.05）；there was no significant difference being found in the comparison of clinical effect between the scraping group and the western medicine group （P＞0.05）. The disappearance time of snoring， nasal obstruction， mouth breathing， tinnitus and other symptoms in the combination group was respectively shorter than that in the scraping group and the western medicine group （P＜0.05）， and the disappearance time of the above symptoms in the scraping group was respectively shorter than that in the western medicine group （P＜0.05）. After treatment， the levels of serum IL-4， IL-6 and TNF-α in the three groups were reduced when compared with those before treatment （P＜0.05），and the levels of serum IL-4，IL-6 and TNF-α in the combination group were lower than those in the scraping group and the western medicine group （P＜0.05）， and the levels of IL-4，IL-6 and TNF-α in the scraping group were lower than those in the western medicine group （P＜0.05）. After treatment， the A/N ratio in the combination group was lower than that in the scraping group and the western medicine group （P＜0.05）， and the A/N ratio in the scraping group was lower than that in the western medicine group（ P＜0.05）. There was no significant difference being found in the comparison of the incidence of adverse reactions among the three groups during the treatment （P＞0.05）. Conclusion： The therapy of Huatan Xiaojie Decoction combined with scraping and prickling method has a significant curative effect on adenoid hypertrophy in children，which can promote the relief of the main symptoms in a short time， and reduce the inflammatory responses and adenoid hypertrophy.