Abstract：Objective：To observe the clinical effect of Danggui Shaoyao Baotai Powder combined with low-molecular-weight heparin sodium on recurrent spontaneous abortion (RSA) of kidney deficiency and blood stasis type with prothrombotic state. Methods： A total of 120 cases of patients with RSA of kidney deficiency and blood stasis type with prothrombotic state were selected and divided into the control group and the trial group according to the random number table method，with 60 cases in each group. The control group was treated with low-molecular-weight heparin sodium injection， and the trial group was additionally treated with Danggui Shaoyao Baotai Powder on this basis. Both groups were treated for six weeks. The success rates of fetal protection， total effective rates， traditional Chinese medicine (TCM) syndrome scores， coagulation function indicators， thromboelastogram (TEG) values， blood routine indexes and uterine artery blood flow parameters were compared between the two groups. Results：After treatment，the success rate of fetal protection in the trial group was 93.33%，which was higher than that of 70.00% in the control group (P＜0.05). After treatment， the total effective rate in the trial group was 96.67%，which was higher than that of 86.67% in the control group (P＜0.05). After treatment，traditional TCM syndrome scores， fibrinogen (FIB) levels， D-dimer (D-D) levels， clot formation rates， maximum clot strength，coagulation comprehensive indexes，red blood cell count，white blood cell count，and the sum of resistance index (RI) in left and right uterine arteries and ratio of peak systolic blood flow velocity to end-diastolic blood flow velocity (S/D) in both uterine arteries were decreased when compared with those before treatment (P＜0.05)， and the TCM syndrome scores， FIB， D-D level， clot formation rate， maximum clot strength，coagulation comprehensive index，red blood cell count，white blood cell count， and the sum of RI in left and right uterine arteries and S/D ratio in both uterine arteries in the trial group were lower than those in the control group (P＜0.05)； the activated partial thromboplastin time (APTT) and coagulation reaction time in the two groups and the clot formation time of blood cells in the trial group were prolonged when compared with those before treatment (P＜0.05)，and the APTT，the coagulation reaction time and the clot formation time of blood cells in the trial group were longer than those in the control group (P＜0.05). Conclusion： Danggui Shaoyao Baotai Powder combined with low-molecular-weight heparin sodium can effectively relieve the clinical symptoms of patients with RSA of kidney deficiency and blood stasis type with prothrombotic state， improve uterine artery blood flow parameters and coagulation function，and increase the success rate of fetal protection.