Abstract： Objective： To observe the clinical effect of point application of self-made Xiaojianzhong Decoction on adult community-acquired pneumonia (CAP) with syndrome of lung-spleen qi deficiency. Methods：A total of 74 cases diagnosed with CAP from July 2021 to July 2023 were selected and divided into two groups according to random number table method，with 37 cases in each group. The control group was given conventional treatment according to CAP diagnosis and treatment guidelines，and the treatment group was treated with point application of self-made Xiaojianzhong Decoction based on the treatment of the control group. The two groups were observed for 10 days. The lung function，arterial blood gas indexes， clinical pulmonary infection score (CPIS)， therapeutic effect and serum procalcitonin (PCT) and C-reactive protein (CRP) levels were compared between the two groups. Results：After 10-day treatment，the vital capacity (VC)， maximum voluntary ventilation (MVV) and forced expiratory volume in one second (FEV1) in the two groups were increased when compared with those before treatment，and the VC，MVV and FEV1 in the treatment group were higher than those in the control group， the difference being significant (P＜ 0.05). After 10-day treatment，the blood oxygen saturation (SaO2) and blood oxygen partial pressure (PaO2) in the two groups were increased when compared with those before treatment，and the partial pressure of carbon dioxide (PaCO2) was decreased when compared with that before treatment， differences being significance (P＜0.05). SaO2 and PaO2 in the treatment group were higher than those in the control group， and PaCO2 in the treatment group was lower than that in the control group，differences being significance (P＜0.05). After 10-day treatment， the CPIS scores in the two groups were decreased when compared with those before treatment， the difference being significance (P＜0.05)， and the CPIS score in the treatment group was lower than that in the control group， the difference was statistically significant(P＜ 0.05). After 10-day treatment，the serum levels of PCT and CRP in the two groups were decreased when compared with those before treatment， and serum levels of PCT and CRP in the treatment group were decreased when compared with those in the control group，differences being significance (P＜0.05). After 10-day treatment，the total effective rate was 97.30% in the treatment group，and 78.38% in the control group， differences being significance (P＜0.05). Conclusion： The point application of self-made Xiaojianzhong Decoction has good clinical effect on adult CAP with syndrome of lung-spleen qi deficiency， which can inhibit inflammation， effectively improve lung function， arterial blood gas indexes and clinical symptoms of patients.