Effect of Auricular Point Sticking and Pressing Combined with Xueshuantong Injection on Dysphagia and Neurological Function in Convalescent Period of Ischemic Stroke
Abstract: Objective: To observe the effects of auricular point sticking and pressing combined with Xueshuantong Injection on dysphagia and neurological function in convalescent period of ischemic stroke. Methods: A total of 82 patients with ischemic stroke with qi deficiency and blood stasis syndrome were selected and divided into the control group and the treatment group according to random number table method,with 41 patients in each group. The control group was given routine treatment,and the treatment group was additionally given auricular point sticking and pressing combined with Xueshuantong Injection based on the treatment of the control group. Both groups were treated for four weeks. The clinical effects in the two groups were compared. The changes in swallowing function [Standardized Swallowing Assessment (SSA), Kubota Water Swallowing Test, Metrohealth scores], neurological function [National Institutes of Health Stroke Scale (NIHSS),Canadian Neurologic Scale (CNS) and Modified Rankin Scale (MRS)],values of hemorheological indexes, serum index values [C-reactive protein (CRP) and interleukin-6 (IL-6)] were compared between the two groups before and after treatment. Results: After four weeks of treatment, the total effective rate of clinical effect was 95.12% in the treatment group and 78.05% in the control group, the difference being significant (P<0.05). After treatment, SSA scores, Kubota Water Swallowing Test scores and Metrohealth scores in the two groups were all decreased when compared with those before treatment (P<0.05), and the above three scores in the treatment group were lower than those in the control group (P<0.05). After treatment,NIHSS scores and MRS Scores in the two groups were decreased when compared with those before treatment (P<0.05),and CNS scores were increased when compared with those before treatment (P<0.05); NIHSS score and MRS score in the treatment group were lower than those in the control group (P<0.05), and CNS score was higher than that in the control group (P< 0.05). After two and four weeks of treatment, whole blood high shear viscosity and platelet aggregation rates in the two groups were reduced when compared with those before treatment (P<0.05), and the whole blood high shear viscosity and platelet aggregation rate in the treatment group were lower than those in the control group in the same time period (P<0.05). After two and four weeks of treatment,the values of CRP and IL-6 in serum in the two groups were decreased when compared with those before treatment (P< 0.05),and the values of CRP and IL-6 in serum in the treatment group were lower than those in the control group in the same time period (P<0.05). Conclusion:Auricular point sticking and pressing combined with Xueshuantong Injection for patients in convalescent period of ischemic stroke can effectively improve their swallowing function,neurological function and hypercoagulable state,reduce inflammatory responses and enhance the clinical effect.