Abstract：Objective：To observe the curative effect of the combination use of Hongteng Baijiang and Danggui Shaoyao Powder and western medicine on endometritis of damp-heat-stasis accumulation type and its effect on levels of inflammatory factors. Methods： A total of 98 patients with endometritis were selected and divided into the reference group and the combination group according to the random number table method， with 49 cases in each group. The reference group was treated with Cefaclor Sustained- Release Capsules， and the combination group was additionally treated with Hongteng Baijiang and with Danggui Shaoyao Powder based on the treatment of the reference group. The clinical effect，incidence of adverse reactions and recurrence were compared between the two groups； the traditional Chinese medicine (TCM) syndrome scores， endometrial thickness， menstruation and levels of tumor necrosis factor-α (TNF-α)，C-reactive protein (CRP)，interleukin-6 (IL-6) and matrix metalloproteinase-9 (MMP-9) were compared before and after treatment between the two groups. Results：The total effective rate was 93.88% in the combination group， higher than that of 79.59% in the reference group (P＜0.05). After treatment， the TCM syndrome scores of irregular menstruation， lower abdominal drop pain， witheryellow complexion and abnormal leucorrhea in the two groups were decreased (P＜0.05)， and the above scores in the combination group were lower than those in the reference group (P＜0.05). After treatment， the endometrial thickness in the two groups was thickened (P＜0.05)，and the endometrial thickness in the combination group was thicker than that in the reference group (P＜0.05). The normal menstrual flow rate and recovery rate of normal menstrual period in the combination group were higher than those in the reference group (P＜0.05)， and the irregular vaginal bleeding rate was lower than that in the reference group (P＜0.05). After treatment，the levels of serum TNF- α，CRP，IL-6 and MMP-9 in the two groups were dwindled，and the above four levels in the combination group were lower than those in the reference group (P＜0.05). The incidence of adverse reactions was 4.08% in the combination group，lower than that of 18.37% in the reference group (P＜0.05). The recurrence rate was 2.17% in the combination group， lower than that of 17.95% in the reference group (P＜0.05). Conclusion：The combination use of Hongteng Baijiang and Danggui Shaoyao Powder has a significant curative effect on endometritis of damp-heat-stasis accumulation type， which can effectively improve the clinical symptoms and menstrual volume， reduce the levels of inflammatory factors，incidence of adverse reactions and recurrence rate.