Abstract： Objective： To observe the clinical effect of Dahuangzhechong Pills combined with Pule'an Tablets on chronic prostatitis (CP) of kidney deficiency and blood stasis type and its impact on lecithin corpuscle and quality of sexual life. Methods：A total of 141 cases of CP patients of kidney deficiency and blood stasis type were selected and divided into the observation group and the control group according to the random number table method，with 71 and 70 cases in each group respectively. The observation group was treated with Dahuangzhechong Pills combined with Pule'an Tablets， and the control group was only taken Pule'an Tablets orally. Clinical effects， traditional Chinese medicine (TCM) syndrome scores， urine routine indicators， number of lecithin corpuscles， and quality of sexual life [International Index of Erectile Function Questionnaire-5 (IIEF-5)] were compared between the two groups. Results： After treatment， the total effective rate was 85.92% in the observation group and 70.00% in the control group， the difference being significant (P＜0.05). After treatment， TCM syndrome scores of fear of cold and cold limbs，sourness and weakness in the waist and knees，perineal pain，lower abdominal pain，lumbosacral pain， medial thigh pain， dribbling after urination， mental lethargy， and impotence and premature ejaculation， as well as the total scores in the two groups were decreased when compared with those before treatment (P＜0.05)， and the above scores in the observation group were lower than those in the control group (P＜0.05). After treatment， urine red blood cells， urine white blood cells， urine acidity and alkalinity， and urine specific gravity in the two groups were improved when compared with those before treatment (P＜0.05)， and the improvements of the above indicators in the observation group were more significant than those in the control group (P＜0.05). After treatment，the number of lecithin corpuscles in the observation group was increased when compared with that before treatment and that in the control group (P＜0.05)， while there was no statistically significant difference in the the the number of lecithin corpuscles in the control group before and after treatment(P＞0.05). After treatment， the scores of each dimension in IIEF-5 as well as the total scores in the two groups were improved when compared with those before treatment (P＜0.05)，and the scores of each dimension and the total score in the observation group were higher than those in the control group (P＜0.05). Conclusion：Dahuangzhechong Pills combined with Pule'an Tablets for CP patients of kidney deficiency and blood stasis type can improve patients' TCM syndromes and urine routine indicators， effectively increase the number of lecithin corpuscles and sexual quality，and have significant clinical effects.