Abstract： Objective： To observe the clinical effect of the combination use of Chinese medicine fumigation and Kirschner wire internal fixation on metacarpal and phalange fractures. Methods： A total of 124 patients with metacarpal and phalange fractures were assigned to the control group and the observation group according to the random number table method，with 62 cases in each group. The control group was treated with open reduction and Kirschner wire internal fixation，and the observation group was additionally treated with Chinese medicine fumigation based on the treatment of the control group. The clinical effects in both groups were evaluated；the traditional Chinese medicine (TCM) syndrome scores，the finger function， and the levels of serum inflammatory factors interleukin-6 (IL-6) and tumor necrosis factor- α (TNF- α) were compared between the two groups；the disappearance time of swelling，pain and ecchymosis，and the recovery time of fractures in both groups were recorded. Results： The excellent-and-good rate was 98.39% in the observation group， higher than that of 88.71% in the control group (P＜0.05). After treatment， the TCM syndrome scores in both groups were reduced when compared with those before treatment，and the above scores in the observation group were lower than those in the control group (P＜ 0.05)；after treatment，the scores of finger function in the two groups were elevated when compared with those before treatment， and the score of finger function in the observation group was higher than that in the control group (P＜0.05). After surgery，the disappearance time of swelling，pain and ecchymosis and the recovery time of fractures in the observation group were shorter than those in the control group (P＜ 0.05). After treatment， the levels of serum IL-6 and TNF- α in the two groups were dwindled when compared with those before treatment (P＜0.05)，and the above two levels in the observation group were lower than those in the control group (P＜0.05). Conclusion： The combination use of Chinese medicine fumigation and Kirschner wire internal fixation has a significant curative effect on metacarpal and phalange fractures， which can promote the improvement of symptoms and vital signs of body and the recovery of fractures，improve the finger function and inhibit the stress of local metacarpal inflammation.