活络柔筋汤加减联合神经肌肉关节促进法治疗缺血性脑卒中后偏瘫临床研究
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R743.3

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Clinical Study on Modified Huoluo Roujin Decoction Combined with Neuromuscular Joint Facilitation for Hemiplegia After Ischemic Stroke
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    摘要:

    目的:观察活络柔筋汤加减联合神经肌肉关节促进法(NJF) 治疗缺血性脑卒中后偏瘫阴虚风动 证的临床疗效。方法:将176例缺血性脑卒中后偏瘫阴虚风动证患者随机分为4组。对照组给予常规康复训练 及治疗,A组另采用NJF,B组另给予活络柔筋汤加减,研究组另给予活络柔筋汤加减联合NJF。治疗前后比较 4组中医症状评分、美国国立卫生研究院卒中量表(NIHSS) 评分、Fugl-Meyer量表(FMA) 评分及改良巴氏 指数(MBI) 评分及血液流变学指标水平,比较4组临床疗效及不良反应。结果:治疗后,4组主症、次症及 总中医症状评分均下降(P<0.05),且研究组低于其余3组(P<0.05),A组、B组均低于对照组(P<0.05)。 治疗后,4组NIHSS评分均降低(P<0.05),且研究组低于其余3组(P<0.05),A组、B组低于对照组(P< 0.05);4 组FMA、MBI 评分均升高(P<0.05),且研究组高于其余3 组(P<0.05),A 组、B 组高于对照 组(P<0.05)。研究组总有效率97.73%,高于其余3组(P<0.05)。治疗后,4组血浆黏度、红细胞沉降率及 红细胞比容均降低(P<0.05),且研究组低于其余3组(P<0.05),A组、B组低于对照组(P<0.05)。4组不 良反应发生率比较,差异无统计学意义(P>0.05)。结论:活络柔筋汤加减联合NJF治疗缺血性脑卒中后偏瘫 阴虚风动证患者疗效显著,可改善症状及血液流变学指标,促进神经功能的恢复,提高肢体运动功能及日常生 活能力,且安全可靠。

    Abstract:

    Abstract:Objective:To observe the clinical effect of modified Huoluo Roujin Decoction combined with neuromuscular joint facilitation (NJF) on hemiplegia after ischemic stroke with stirring of wind due to yin deficiency syndrome. Methods:A total of 176 cases of patients with hemiplegia after ischemic stroke with stirring of wind due to yin deficiency syndrome were randomly divided into four groups. The control group received routine rehabilitation training and treatment,group A was additionally treated with NJF,group B was additionally treated with modified Huoluo Roujin Decoction, and the study group was additionally treated with modified Huoluo Roujin Decoction combined with NJF. Compared the traditional Chinese medicine symptom scores, National Institutes of Health Stroke Scale (NIHSS) scores, Fugl Meyer Scale (FMA) scores, Modified Barthel Index (MBI) scores, and hemorheological index levels between the four groups before and after treatment, and compared the clinical efficacy and adverse reactions in the four groups. Results: After treatment, the scores of main symptoms, secondary symptoms, and total traditional Chinese medicine symptoms in the four groups were all decreased (P<0.05),the scores in the study group were lower than those in the other three groups (P<0.05),and the scores in groups A and B were both lower than those in the control group (P<0.05). After treatment,the NIHSS scores in all the four groups were decreased (P<0.05), the score in the study group was lower than those in the other three groups (P<0.05),and the scores in groups A and B were lower than that in the control group (P<0.05). The FMA and MBI scores in the four groups were all increased (P<0.05),the scores in the study group were higher than those in the other three groups (P<0.05),and the scores in groups A and B were higher than those in the control group (P<0.05). The total effective rate was 97.73% in the study group, which was higher than those in the other three groups (P<0.05). After treatment, the plasma viscosity, erythrocyte sedimentation rates, and hematocrit in the four groups were all decreased (P<0.05), the indexes in the study group were lower than those in the other three groups (P<0.05),and the indexes in groups A and B were lower than those in the control group (P<0.05). There was no significant difference in the incidence of adverse reactions among the four groups (P>0.05). Conclusion: Modified Huoluo Roujin Decoction combined with NJF has a significant therapeutic effect on patients with hemiplegia after ischemic stroke with stirring of wind due to yin deficiency syndrome. It can improve symptoms and hemorheological indicators, promote the recovery of neurological function, improve limb motor function and daily living ability,and is safe and reliable.

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路小坦,高希言.活络柔筋汤加减联合神经肌肉关节促进法治疗缺血性脑卒中后偏瘫临床研究[J].新中医,2024,56(17):22-27

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  • 在线发布日期: 2024-09-11
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