Abstract：This paper introduces the clinical experience of Professor PENG Jianhong using the method of nourishing yin and subduing yang in the treatment of primary Sjogren's syndrome. Primary Sjogen's syndrome belongs to the category of dry impediment in Chinese medicine. Professor PENG holds that dry impediment is not simply a deficiency of body fluids， but rather characterized by insufficient yin essence and yin deficiency with yang hyperactivity. The clinical practice follows the guidance of the core idea of HE Yanshen， a famous experienced Chinese medicine physician， in using the method of nourishing yin and subduing yang to treat diseases of yin deficiency with yang hyperactivity；in the treatment of dry diseases with the method of nourishing yin and subduing yang， the common formula is Sanjia Fumai Decoction， based on which Chinese medicinals of nourishing the liver and kidney，boosting qi and fortifying the spleen， and invigorating blood and unblocking the collaterals can be modified.