Abstract: Objective: To observe the clinical effect of catgut embedment in acupoint combined with dynamic moxibustion for functional dyspepsia. Methods: A total of 150 cases of patients with functional dyspepsia of the spleen-stomach deficiency type were enrolled in the study and divided into the control group A, the control group B, and the trial group according to the random number table method. The control group A was treated with catgut embedment in acupoint, the control group B was treated with dynamic moxibustion, and the trial group was treated with catgut embedment in acupoint and dynamic moxibustion. All the three groups were treated for four weeks. The scores of the Gastrointestinal Symptom Rating Scale (GSRS), Digestive Symptom Scale (DSS), Functional Digestive Disorders Quality of Life Questionnaire (FDDQL), and Short Form Health Survey (SF-36), and traditional Chinese medicine (TCM) syndrome scores were evaluated before and after treatment. Clinical effects were compared between the three groups. Adverse reactions during treatment were observed and recorded. Results:After treatment, the total effective rate in the trial group was higher than those in the control group A and the control group B (P<0.05). There was no significant difference in the total effective rates between the control group A and the control group B (P>0.05). The GSRS scores and DSS scores in the three groups were decreased when compared with those before treatment, differences being significant (P<0.05). The scores of GSRS and DSS in the trial group were lower than those in the control group A and the control group B, differences being significant (P<0.05). There was no significant difference in the scores of GSRS and DSS between the control group A and the control group B (P>0.05). The scores of FDDQL in the three groups were decreased when compared with those before treatment, and SF-36 scores were increased when compared with those before treatment,differences being significant (P<0.05). FDDQL score in the trial group was lower than those in the control group A and the control group B,and SF-36 score was higher than those in the other two groups,differences being significant (P<0.05). There was no significant difference in the scores of FDDQL and SF-36 between the control group A and the control group B (P>0.05). The scores of the six TCM syndromes including abdominal distension and fullness, preference to warmth and pressure, loose stools,poor appetite,lack of qi and lazy speech,low speech and the total score in the three groups were decreased when compared with those before treatment, differences being significant (P<0.05). The six TCM syndrome scores and the total score in the trial group were lower than those in the control group A and the control group B, differences being significant (P<0.05). There was no significant difference in the six TCM syndrome scores and total scores between the control group A and B (P>0.05). No significant difference was found in the comparison of the incidence of adverse reactions among the three groups (P> 0.05). Conclusion:In the treatment of functional dyspepsia,catgut embedment in acupoint combined with dynamic moxibustion can strengthen curative effects,promote recovery,and improve quality of life,with good safety.