Abstract: Objective: To observe the effect of modified Bufei Ejiao Decoction and Baihe Gujin Decoction combined with western medicine on bronchiectasis in senile patients. Methods: A total of 206 cases of senile patients who had bronchiectasis with yin deficiency and phlegm-heat syndrome were randomly divided into the combination group and the western medicine group. Both groups were treated with conventional western medicine, and the combination group was additionally treated with modified Bufei Ejiao Decoction and Baihe Gujin Decoction. Both groups were treated for two weeks. Traditional Chinese medicine (TCM) syndrome scores, degree of dyspnea [scores of modified Medical Research Council (mMRC) and Bronchiectasia Severity Index (BSI)], pulmonary ventilation function indicators [the forced expiratory volume in one second (FEV1),forced vital capacity (FVC),the ratio of FEV1 to FVC (FEV1/ FVC),and maximal voluntary ventilation (MVV)], inflammatory markers [procalcitonin (PCT), interleukin- 17 (IL-17),and erythrocyte sedimentation rates] before and after two weeks of treatment were compared. The time for lung rale reduction, relief of expectoration and panting, and incidence of adverse reactions were recorded. Clinical effects were compared between the two groups. Results: After two weeks of treatment,the total effective rate in the combination group was higher than that in the western medicine group (P<0.05). The comparison of curative effects between the two groups showed significance in the difference (P<0.05). The scores of the main symptoms and secondary symptoms of TCM syndrome in the two groups were decreased when compared with those before treatment (P<0.05). The scores of the main symptoms and secondary symptoms of TCM syndrome in the combination group were lower than those in the western medicine group (P<0.05). The time for lung rale reduction and relief of expectoration and panting in the combination group were earlier than those in the western medicine group (P<0.05). The scores of mMRC and BSI in the two groups were declined when compared with those before treatment (P< 0.05), and the scores of mMRC and BSI in the combination group were lower than those in the western medicine group (P<0.05). The values of FEV1, FVC, FEV1/FVC, and MVV in the two groups were increased when compared with those before treatment (P<0.05), and the four indicators in the combination group were higher than those in the western medicine group (P<0.05). The levels of PCT and IL-17, and erythrocyte sedimentation rates in the two groups were reduced when compared with those before treatment (P<0.05),and the three indicators in the combination group were lower than those in the western medicine group (P<0.05). Conclusion:Modified Bufei Ejiao Decoction and Baihe Gujin Decoction combined with western medicine can effectively relieve the clinical symptoms and lung ventilation function of senile patients with bronchiectasis with yin deficiency, improve phlegm-heat syndrome, and reduce inflammatory reactions with good safety.