Abstract： Objective： To explore the effect of the therapy of Ditan Zhuyu Decoction combined with western medicine on ischemic stroke of phlegm-blood stasis obstructing the collaterals type in convalescence stage and its effects on hemorheology and blood lipid. Methods：A total of 60 patients with ischemic stroke of phlegm-blood stasis obstructing the collaterals type in convalescence stage were selected and divided into the control group and the treatment group according to the random number table method， with 30 cases in each group. The control group was treated with western medicine and rehabilitation， and the treatment group was additionally treated with Ditan Zhuyu Decoction based on the treatment of the control group. The clinical effects and incidence of adverse reactions，and the changes of traditional Chinese medicine syndrome scores， hemorheology indexes， scores of National Institute of Health Stroke Scale (NIHSS)， Barthel Index (BI)， and levels of blood lipid (TC， TG， LDL-C and HDL-C were compared before and after treatment between the two groups. Results： The total clinical effective rate was 80.00% in the control group and 96.67% in the treatment group with significant difference (P＜ 0.05). After treatment， the scores of hemiplegia， deviation of mouth and tongue， hemianesthesia， and dizziness in the two groups were decreased，and the above four scores in treatment group were lower than those in control group (P＜0.05). After treatment，the values of whole blood viscosity，plasma viscosity and fibrinogen in the two groups were decreased， and the above three values in treatment group were lower than those in control group (P＜0.05). After treatment，the NIHSS scores in the two groups were decreased (P＜0.05)， and BI scores were increased(P＜0.05)； the NIHSS score in treatment group was lower than that in control group (P＜0.05)， and the BI score was higher than that in control group (P＜0.05). After treatment， the levels of TC， TG and LDL-C in wo groups were decreased (P＜0.05)， and the HDL-C levels were increased (P＜0.05)；the levels of TC，TG and LDL-C in the treatment group were lower than those in control group (P＜0.05)，and the HDL-C level was higher than that in control group (P＜0.05). The rate of adverse reactions was 6.67% in the control group and 3.33% in the treatment group，there being no significance in the difference (P＞0.05). Conclusion： The therapy of Ditan Zhuyu Decoction and western medicine has a definite curative effect on ischemic stroke of phlegm-blood stasis obstructing the collaterals type in convalescence stage， which can mitigate the clinical symptoms， improve the hemorheology indexes，nerve function and activity of daily living，and regulate the level of blood lipid with great safety.