Abstract： Objective： To observe the clinical effect of Modified Sijunzi Decoction assisting routine western medicine on gastrointestinal dysfunction after surgery for acute appendicitis in children. Methods： A total of 86 cases of children with gastrointestinal dysfunction after surgery for acute appendicitis were divided into the combination group and the reference group according to the random number table method， with 43 cases in each group. The reference group was treated with routine western medicine， and the combination group was additionally treated with Modified Sijunzi Decoction based on routine western medicine. Both groups were treated for three days. Traditional Chinese medicine syndrome scores and gastrointestinal hormone levels before and after treatment were compared between the two groups. The clinical effects and symptom remission time were compared between the two groups. Results： The total clinical effective rate was 97.67% in the combination group， higher than that of 83.72% in the reference group (P＜0.05). After treatment， the scores of traditional Chinese medicine syndromes like epigastric fullness， loss of appetite， fatigue and weakness， nausea and vomiting， and loose stool were all decreased in the two groups were decreased (P＜0.05)， and the scores in the combination group were lower than those in the reference group (P＜0.05). The disappearance time of abdominal pain and abdominal distension，the first exhaust time，the bowel sound recovery time and the first defecation time in the combination group were shorter than those in the reference group (P＜0.05). After treatment， the levels of plasma motilin (MTL) and serum gastrin (GAS) in the two groups were increased (P＜0.05)，and the levels in the combination group were higher than those in the reference group (P＜0.05). Conclusion： Modified Sijunzi Decoction assisting routine western medicine has a significant curative effect in treating gastrointestinal dysfunction after surgery for acute appendicitis in children， which can effectively promote the relief of symptoms and signs and regulate the levels of gastrointestinal hormones.