Abstract: Objective: To observe the clinical effect of Wenyang Huayin Decoction combined with modulated medium frequency electrotherapy on polycystic ovary syndrome with hyperandrogenism (PCOSHA). Methods:EXCEL software was used to generate corresponding random numbers and at the ratio of 1∶ 1∶1,60 patients with PCOS-HA were divided into the Wenyang Huayin Decoction group,the Wenyang Huayin Decoction combined with modulated medium frequency electrotherapy group (the combination group) and the western medicine group with 20 cases in each group. The western medicine group was treated with Ethinylestradiol and Cyproterone Acetate Tablets;the Wenyang Huayin Decoction group was treated with Wenyang Huayin Decoction, and the combination group was treated with Wenyang Huayin Decoction combined with modulated medium frequency electrotherapy. The three groups were treated for six menstrual cycles continuously. The changes of menstrual cycle,testosterone (T),luteinizing hormone (LH),follicle stimulating hormone (FSH),scores of Ferriman-Gallway (F-G),and score of acne Rosefiled were evaluated and compared before and after treatment. Results:After three months of treatment,the total effective rate of menstruation regulation was 35.0% in the Wenyang Huayin Decoction group,45.0% in the combination group,and 85.0% in the western medicine group. After six months of treatment,the total effective rate of menstruation regulation was 65.0% in the Wenyang Huayin Decoction group,75.0% in the combination group, and 90.0% in the western medicine group; after three months of follow-up, the total effective rate of menstruation regulation was 50.0% in the Wenyang Huayin Decoction group, 70.0% in the combination group, and 30.0% in the western medicine group. After the end of treatment, the levels of T,LH/FSH,scores of F-G and Rosefiled in the three groups were decreased when compared with those before treatment,differences being significant (P<0.05). After the end of treatment,there was no significant difference in the levels of T, LH/FSH, and F-G score between the three groups (P>0.05). After the end of treatment, there was significant difference in Rosefiled score between the three groups (P<0.05);there was no significant difference in Rosefiled score between the Wenyang Huayin Decoction group and the combination group (P>0.05), and the Rosefiled scores in the two groups were lower than those in the western medicine group (P<0.05). Conclusion:Wenyang Huayin Decoction and the therapy of Wenyang Huayin Decoction combined with modulated medium frequency electrotherapy for PCOS-HA can adjust the reproductive hormone levels and improve clinical symptoms, and the combined treatment has better long-term effect than Ethinylestradiol and Cyproterone Acetate Tablets.