Abstract： Objective： To explore the medication rules of ZHANG Jingyue in treating strangury with turbid discharge based on data mining technology. Methods： The information of prescriptions and medicinals for treating strangury with turbid discharge by ZHANG Jingyue in Jing Yue Quan Shu (The Complete Works of ZHANG Jingyue) was collected and standardized， and a database was established. SPSS Modeler18.0， SPSS Statistics26.0， Cytoscape3.9.1 and other softwares were used for medicinal frequency， frequency distribution analysis， medicinal association and cluster analysis. Results： A total of 55 prescriptions were obtained；105 kinds of Chinese medicinals were used，and the total frequency of the 105 kinds of Chinese medicinals was 386 times. Among 28 high-frequency Chinese medicinals (frequency≥ 5 times)，Poria was at the highest frequency. According to the statistics of effects，there were 13 kinds of Chinese medicinals for supplementing deficiency， ranking the first， followed by 6 kinds of Chinese medicinals for promoting urination and percolating dampness. According to the medicinal association analysis，8 medicinal association rules were obtained，such as Poria-Polygalae Radix and Ginseng Radix et Rhizoma， Dioscoreae Rhizoma-Corni Fructus， and so on. The drug association mesh obtained higher degree of medicinal pairs，such as Poria-Ginseng Radix et Rhizoma，Dioscoreae Rhizoma-Corni Fructus， Poria-Polygalae Radix，Akebiae Caulis-Gardeniae Fructus，and so on. Cluster analysis obtained three core prescriptions，namely，“Dioscoreae Rhizoma，Corni Fructus，Rehmanniae Radix Praeparata，Cinnamomi Cortex， Cuscutae Semen， Allii Tuberosi Semen， Eucommiae Cortex， Morindae Officinalis Radix， Achyranthis Bidentatae Radix，Schisandrae Chinensis Fructus，Moutan Cortex”“Angelicae Sinensis Radix， Atractylodis Macrocephalae Rhizoma， Ginseng Radix et Rhizoma， Polygalae Radix， Poria， Glycyrrhizae Radix et Rhizoma Praeparata cum Melle”“Scutellariae Radix， Ophiopogonis Radix， Rehmanniae Radix， Alismatis Rhizoma， Polyporus， Plantaginis Semen， Junci Medulla， Akebiae Caulis， Gardeniae Fructus， Glycyrrhizae Radix et Rhizoma ”. Conclusion： ZHANG Jingyue advocated to treat strangury with turbid discharge by supplementing deficiency to treat the root and by draining dampness to treat the branch. When supplementing deficiency to treat the root，the spleen and kidney is emphasized. When treating strangury with turbid discharge of spleen-kidney depletion type， the main treatment is to warm and supplement， and to raise center qi，supplemented by percolating and draining dampness with mild medicinals. Besides， according to the syndrome characteristics，the medicinals for astringing，calming the heart，and assisting yang were applied. When draining dampness to treat the branch， it is not limited to use cold or heat medicinals； the first recommendation is to use Poria to percolate and drain dampness. When treating strangury with turbid discharge of bladder damp-heat type， the main treatment is to clear heat and drain dampness，flexibly supplemented by Achyranthis Bidentatae Radix to invigorate blood and relieve strangury.