Abstract： The saying of “fluid of the spleen is thin saliva， and fluid of the kidney is thick saliva” emphasizes the key role of the spleen and kidney in the generation， distribution， and excretion of saliva. The pathogenesis of sialorrhea always belongs to spleen and kidney deficiency；or spleen qi fails to ascend， mouth lacks fluids， and turbid pathogen dries up； or spleen yang depletes， earth fails to control water， and oral fluid fails to transport； or spleen deficiency fails to contain， mouth and lip become flaccid， and saliva overflows；or due to kidney yin depletion，deficiency-heat spleen，and fire pressure in the body；or kidney yang depletion， unfavorable closing of the door， and convergence of the mouth and saliva； or kidney qi depletion， congenital deficiency， and cessation of oral fluid. In clinical differentiation and treatment， attention should be paid to the core pathogenesis of spleen-kidney depletion， with fortifying the spleen and stopping salivation， reinforcing kidney and absorbing saliva as the treatment principle. The methods can be used to promote the balance and stability of body fluid metabolism， such as tonifying qi and fortifying the spleen，rectifying qi and removing turbidity，promoting spleen circulation，warming yang and dissolving rheum， supplementing the center and boosting qi， fortifying the spleen and absorbing saliva， nourishing the kidney and enriching yin， removing turbidity and promoting urination， supplementing kidney qi， and reducing rheum and eliminating pathogenic factors， thereby gradually improving salivation.