Abstract: This article discussed the clinical approach to treating chronic diarrhea with the theory of harmonization with warm medicinals. The disease location of chronic diarrhea lies in the large intestine, involving both the liver and spleen, especially closely related to the spleen and stomach function. Various reasons lead to the devitalized spleen yang, which is an important pathogenesis of recurrent diarrhea. In terms of the treatment, in addition to harmonizing the liver and spleen, fortifying the spleen and harmonizing the stomach,and dispelling dampness in the stomach,it is advisable to use warm medicinals for harmonization,either warming and unblocking and warming and supplementing.