Abstract： Objective： To observe the clinical effect of umbilical moxibustion on ginger combined with Weifuchun Capsules for chronic atrophic gastritis (CAG) of spleen-stomach weakness type. Methods： A total of 138 cases of CAG patients of spleen-stomach weakness type were selected and divided into the control group A， the control group B， and the trial group， with 46 cases in each group. One case was excluded from each group， and finally 45 cases were included in each group. The control group A was treated with umbilical moxibustion on ginger， the control group B was treated with Weifuchun Capsules， and the trial group was treated with umbilical moxibustion on ginger combined with Weifuchun Capsules. The three groups were treated for 4 weeks. Traditional Chinese Medicine syndrome effects， as well as gastric mucosal histopathological scores and gastrointestinal hormone levels were compared before and after treatment among the three groups. Adverse reactions incidence rate were recorded. Results： After treatment，there was significant difference in the comparison of the total effective rates among the three groups (P＜0.05). The total effective rate was 91.11% in the trial group，higher than that of 68.89% in the control group A and 77.78% in the control group B (P＜0.05). The scores of chronic inflammation，epithelial metaplasia， glandular atrophy， and atypical hyperplasia in the three groups were decreased when compared with those before treatment (P＜0.05)， and the scores of chronic inflammation， epithelial metaplasia， glandular atrophy， and atypical hyperplasia in the trial group were lower than those in the control group A and the control group B (P＜0.05)； there was no significance difference in the scores of chronic inflammation， epithelial metaplasia， glandular atrophy， and atypical hyperplasia between the control group A and the control group B (P＞0.05). The levels of gastrin (GAS)，pepsinogen Ⅱ(PGⅡ)，and motilin (MTL) in serum in the three groups were increased when compared with those before treatment (P＜ 0.05)；the levels of GAS，PGⅡ，and MTL in serum in the trial group were higher than those in the control group A and the control group B (P＜0.05)；there was no significant difference in the levels of GAS，PGⅡ， and MTL in serum between the control group A and the control group B (P＞0.05). The incidence of adverse reactions was 8.89% in the trial group，6.67% in the control group A，and 2.22% in the control group B， there being no significance in the difference (P＞0.05). Conclusion： Umbilical moxibustion on ginger combined with Weifuchun Capsules can achieve significant curative effects in the treatment of CAG of spleen-stomach weakness type， and effectively improve gastric mucosal histopathological states and gastrointestinal hormone levels with good safety.