Abstract: Objective: To observe the clinical effect of cross moxibustion combined with western medicine on stress urinary incontinence in postmenopausal. Methods: A total of 102 cases of postmenopausal patients with stress urinary incontinence were divided into the control group and the trial group according to the random number table method,with 51 cases in each group. The control group was treated with conventional western medicine, and the trial group was additionally treated with cross moxibustion based on the treatment of the control group. Both groups were treated for 4 weeks. Traditional Chinese medicine (TCM) syndrome scores, scores of the International Consultation on Incontinence Questionnaire - Urinary Incontinence Short Form (ICI-Q-SF), urodynamic indicators [Maximum detrusor pressure (MDP),abdominal leak point pressure (ALPP),and maximum urethral closure pressure (MUCP)], and urinary leakage volume tested by 1-hour pad test were compared between the two groups before and after treatment. Clinical effects and treatment safety were evaluated in the two groups. Results:During the treatment,2 cases were excluded from both groups,and there were 49 cases who completed the study in each group. The total effective rate was 93.88% in the trial group,higher than that of 79.59% in the control group (P<0.05). After 4 weeks of treatment,the scores of each dimensions and the total scores of ICI-QSF, urinary leakage volume tested by 1-hour pad test,and TCM syndrome scores were lower than those before treatment (P<0.05); MDP,ALPP,and MUCP were higher than those before treatment (P<0.05); TCM syndrome scores,urinary leakage volume tested by 1-hour pad test and ICI-Q-SF scores in the trial group were lower than those in the control group (P<0.05), and urodynamic indicators in the trial group were higher than those in the control group (P<0.05). There was no significant difference being found in the incidence of adverse reactions between the two groups (P>0.05). Conclusion: Cross moxibustion combined with western medicine has significant curative effects in the treatment of stress urinary incontinence in postmenopausal women, and can improve urodynamic indicators and reduce clinical symptoms with high safety.