Abstract： This paper introduces CHEN Zhiqiang's experience in treating chronic prostatitis from deficiency and stasis based on syndrome differentiation. In the treatment of chronic prostatitis， CHEN Zhiqiang emphasized the combination of new-onset illness and prolonged illness， and of local syndrome differentiation and microscopic syndrome differentiation. The disease starts with stasis and stasis continues throughout the disease. Prolonged illness is dominated by deficiency， and reflects deficiency-excess complex. In the treatment， CHEN Zhiqiang uses the four methods of clearing， transforming， unblocking and supplementing， that is， clearing heat and dissolving stasis to unblock collaterals， moving qi and dissolving stasis to unblock collaterals，invigorating blood and dissolving stasis to unblock collaterals，and supplementing deficiency and dissolving stasis to unblock collaterals. He also takes care of the spleen and the stomach， and combines with changing bad living habits， so as to achieve the combination of prevention and treatment，and treat the root and branch simultaneously.