Abstract：Objective：To observe the effect of the therapy of moxa-salt package combined with point application and auricular point seed-pressing on the quality of life and adverse reactions in hematologic tumor patients undergoing chemotherapy. Methods： A total of 150 patients with hematologic tumors undergoing chemotherapy were randomly divided into the observation group and the control group， with 75 patients in each group. The two groups were treated with Tropisetron Hydrochloride Injection， Magnesium Isoglycyrrhizinate Injection and Human Blood Albumin， and the observation group was additionally treated with moxa-salt package combined with point application and auricular point seedpressing. The incidence of chemotherapy adverse reactions，scores of Herth Hope Index (HHI) and Quality of Life Instruments for Cancer Patients-Leukemia (QLICP-LE) were compared between the two groups. Results： The total effective rate was 80.00% in the observation group and 62.67% in the control group， the difference being significant (P＜0.05).The incidence of gastrointestinal adverse reactions was 60.00% in the observation group and 77.33% in the control group， the difference being significant (P＜0.05). There was no significant difference in the incidence of myelosuppression， mucosal toxicity， liver and kidney damage，allergy and other reactions between the two groups (P＞0.05). The total incidence of nausea and vomiting was 46.67% in the observation group and 66.67% in the control group， the difference being significant (P＜0.05). After treatment， the HHI and QLICP-LE scores in the two groups were increased when compared with those before treatment (P＜0.05)， and the HHI and QLICP-LE scores in the observation group were higher than those in the control group (P＜0.05). Conclusion： The therapy of conventional western medicine combined with moxa-salt package， point application and auricular point seed-pressing can reduce the incidence of chemotherapy nausea and vomiting in hematologic tumor patients undergoing chemotherapy， improve the quality of life，enhance their chemotherapy attitude and survival belief，and have a definite clinical effect.