Abstract:Objective:To observe the curative effect of Huoxue Yixin Prescription combined with point application on chronic heart failure (CHF) of qi stagnation and blood stasis type. Methods:A total of 94 cases of CHF patients of qi stagnation and blood stasis type were selected and randomly divided into the combination group and the control group,with 47 cases in each group. The control group was treated with routine western medicine, and the combination group was additionally treated with Huoxue Yixin Prescription combined with point application based on routine western medicine treatment. After 4 weeks of continuous treatment,the clinical effects and incidence of adverse reactions were compared between the two groups. The traditional Chinese medicine (TCM) syndrome scores, heart function indexes [left ventricular ejection fraction (LVEF),left ventricular end systolic diameter (LVESd),and left ventricular end diastolic diameter (LVEDd)], Cardiac Risk Index (Lee Criteria) scores, 6-minute walk test (6MWT), and Minnesota Living with Heart Failure Questionnaire (MLHFQ) scores were compared before and after treatment. Results: The total effective rate was 95.75% in the combination group, higher than that of 82.98% in the control group, the difference being significant (P<0.05). After treatment, the main and secondary symptom scores of TCM syndromes in the two groups were decreased when compared with those before treatment (P<0.05),and the main and secondary symptom scores in the combination group were lower than those in the control group (P<0.05). After treatment, the Lee Criteria scores in the two groups were decreased when compared with those before treatment (P<0.05), and Lee Criteria score in the combination group was lower than that in the control group (P<0.05). The 6MWT was prolonged when compared with that before treatment (P<0.05),and 6MWT in the combination group was longer than that in the control group (P<0.05). After treatment, the LVEF levels in the two groups were increased when compared with those before treatment (P<0.05),and LVESd and LVEDd were shortened when compared with those before treatment (P<0.05), the LVEF in the combination group was higher than that in the control group (P<0.05), and LVESd and LVEDd were shorter than those in the control group (P<0.05). After treatment,the MLHFQ scores in the two groups were decreased when compared with those before treatment (P<0.05), and the MLHFQ score in the combination group was lower than that in the control group (P<0.05). During the treatment period, the incidence of adverse reactions was 8.51% in the combination group and 6.38% in the control group,there being no significant difference between the two groups (P>0.05). Conclusion: The combination of Huoxue Yixin Prescription combined with point application has a significant curative effect on CHF of qi stagnation and blood stasis type,which can further alleviate clinical symptoms,improve heart function and quality of life,with good safety.