Abstract：Objective：To study the medication rules of Chinese medicine fumigation for vaginitis based on data mining. Methods：The randomized controlled clinical literatures on Chinese medicine fumigation for vaginitis were searched and collected from China National Knowledge Infrastructure (CNKI)，China Science and Technology Journal Database (VIP)， China Biology Medicine disc (CBM) and China Science Periodical Database (Wanfang) from the establishment day of the databases to 24th February，2023 and the database was established； the use frequency， nature， flavor， channel entry and curative effects of Chinese medicinals were counted and highly-used Chinese medicinals were given association rule analysis，cluster analysis and complex network analysis. Results： A total of valid 156 prescriptions were screened out； 123 Chinese medicinals were involved which were used for 1 344 times in total. Among them，23 Chinese medicinals were highly used for Chinese medicine fumigation for vaginitis，including Sophorae Flavescentis Radix， Cnidii Fructus， Phellodendri Chinensis Cortex， Stemonae Radix， Dictamni Cortex and Kochiae Fructus；they were mainly mild and warm in nature，and bitter，sweet and pungent in flavor，with main channel entries to the liver and lung. Based on the association rule analysis，the highly-used core medicinal pair was Cnidii Fructus-Sophorae Flavescentis Radix；the combination of 3 medicinals was Cnidii Fructus- Phellodendri Chinensis Cortex-Sophorae Flavescentis Radix， the combination of 4 medicinals was Phellodendri Chinensis Cortex-Kochiae Fructus-Cnidii Fructus-Sophorae Flavescentis Radix； the combination of 5 medicinals was Cnidii Fructus-Kochiae Fructus-Dictamni Cortex-Phellodendri Chinensis Cortex-Sophorae Flavescentis Radix， and the combination of 6 medicinals was Dictamni Cortex-Kochiae Fructus - Stemonae Radix-Phellodendri Chinensis Cortex-Cnidii Fructus-Sophorae Flavescentis Radix. The cluster analysis suggested 3 correlated medicinal combinations ； the complex network analysis showed 7 core Chinese medicinals in the prescriptions of Chinese medicine fumigation for vaginitis， including Sophorae Flavescentis Radix， Cnidii Fructus， Phellodendri Chinensis Cortex， Kochiae Fructus， Dictamni Cortex， Smilacis Glabrae Rhizoma and Stemonae Radix. Conclusion： In the prescriptions of Chinese medicine fumigation for vaginitis，medicinals for clearing heat，supplementing deficiency，and promoting urination and percolating dampness are mainly used under the treatment methods of clearing heat and drying dampness， and killing worms and relieving itching， supplemented with tonifying and boosting the liver and kidney.