Abstract：Objective：To observe the clinical effect of Chinese herbal fumigation combined with nerve block on patients with lumbar disc herniation (LDH). Methods：A total of 120 cases of LDH patients were selected and divided into the observation group and the control group according to the random number table method，with 60 cases in each group. The observation group was treated with Chinese herbal fumigation combined with nerve block therapy， and the control group was simply given nerve block therapy. The clinical effects were compared between the two groups； traditional Chinese medicine (TCM) syndrome scores， Oswestry Disability Index (ODI) scores， Visual Analogue Scale (VAS) scores， and Japanese Orthopaedic Association (JOA) scores were compared before and after treatment between the two groups. Results：After treatment，the total effective rate was 91.67% in the observation group，higher than that of 78.33% in the control group (P＜0.05). After treatment，the scores of TCM syndrome such as soreness in waist and legs， lumbar stiffness and local tenderness in the two groups were decreased (P＜0.05)， and the above scores in the observation group were lower than those in the control group (P＜0.05). After treatment，the scores of ODI and VAS in the two groups were decreased (P＜0.05)，and the scores in the observation group were lower than those in the control group (P＜0.05)； JOA scores in the two groups were increased (P＜0.05)，and the score in the observation group was higher than that in the control group (P＜0.05). Conclusion： When compared with simple nerve block therapy， Chinese herbal fumigation combined with nerve block therapy has a better effect on alleviating soreness and pain in waist and legs， relieving lumbar stiffness and local tenderness and improving lumbar movement function in LDH patients.