Abstract：Objective：To observe the clinical effect of adjuvant treatment of Qingre Shenshi Decoction on benign prostatic hyperplasia (BPH) after green- light laser photoselective vaporisation of the prostate (PVP). Methods： A total of 150 cases of BPH patients who underwent PVP were divided into the the observation group and the control group by random number table， with 75 cases in each group. Both groups were treated with PVP； after operation， the control group was additionally treated with Tylosine Hydrochloride Sustained Release Tablets，and the observation group was additionally treated with Qingre Shenshi Decoction. Before and after treatment，the traditional Chinese medicine (TCM) syndrome scores， International prostate symptom score (IPSS score)，urinary function，Quality of life (QOL) scores，and sex hormone levels were compared in two groups. The clinical effects and rate of side reactions were analyzed. Results：The total effective rate was 92.00% in observation group，higher than that of 78.67% in control group (P＜0.05). After treatment， the scores of TCM syndromes， IPSS， and QOL in two groups were decreased(P＜0.05)，and the above indexes in observation group were lower compared with control group (P＜0.05). After treatment， the daytime urination frequency， nighttime urination frequency， urgent urination frequency，post-void residual volume (PVR)，luteinizing hormone (LH)，and estradiol (E2) levels in the two groups were decreased (P＜0.05)，and the maximum urinary flow rate (Qmax)，testosterone (T)， and prolactin (PRL) levels were increased (P＜0.05); the daytime urination frequency， nighttime urination frequency， urgent urination frequency， PVR， LH， and E2 levels in observation group were lower(P＜ 0.05)，and the levels of Qmax，T，and PRL were higher than those in the control group (P＜0.05). The rate of side reactions was no difference in two groups (P＞0.05). Conclusion：The adjuvant treatment of Qingre Shenshi Decoction for BPH after PVP has a definite curative effect，which can improve the urinary function and sex hormone levels of patients，and improve their quality of life，with high safety.