Abstract:Objective:To observe the effect of Shengyang Yiwei Decoction on proximal gastric diastole and gastric emptying in patients with functional dyspepsia. Methods:A total of 103 patients with functional dyspepsia were selected as the study objects and divided into the observation group and the control group by random number table method,with 52 cases and 51 cases in each group respectively. The control group was treated with Domperidone Tablets,and the observation group was additionally treated with Shengyang Yiwei Decoction based on the treatment of the control group. All patients were treated for 2 weeks. The clinical effects and adverse reactions in the two groups were compared, and the traditional Chinese medicine (TCM) syndrome scores, proximal gastric diastolic function indexes, gastric emptying function and serum levels of motilin (MTL) and gastrin (GAS) were compared before and after treatment between the two groups. Results: The total effective rate was 94.00% in the observation group, higher than that of 76.47% in the control group (P<0.05). After treatment, the TCM syndrome scores of stomach cavity distention and pain or impediment and sealed moistening, fatigue and weakness, withered- yellow complexion,belching and hiccups,poor appetite,and thin and unformed stool were all decreased in the two groups (P<0.05),and the above scores in the observation group were lower than those in the control group (P<0.05). After treatment,the gastric fundus gas scores in both groups were decreased (P<0.05), and the gas score in the observation group was lower than that in the control group (P<0.05). After treatment,10 minutes after trial diet (T2),30 minutes after trial diet (T3) and 60 minutes after trial diet (T4), the proximal gastric volume of both groups was respectively decreased (P<0.05), and at T3 and T4, the proximal gastric volume of the observation group was respectively smaller than that of the control group (P< 0.05). After treatment,the gastric emptying rates in both groups were increased (P<0.05),and the rate in the observation group was higher than in the control group (P<0.05). After treatment,the levels of MTL and GAS were increased in both groups (P<0.05),and the two levels in the observation group were higher than those in the control group (P<0.05). Conclusion:Shengyang Yiwei Decoction can effectively improve the proximal gastric diastole and gastric emptying function in patients with functional dyspepsia, relieve clinical symptoms and improve clinical effect.