Abstract： This paper introduces Professor YANG Wei's clinical experience in treating anorectal diseases with the theory of "anus as envoy of five zang- organs". Professor YANG Wei believes that the normal opening and closing of the anus is closely related to the normal play of the functions of the five zangorgans of the liver，heart，spleen，lung and kidney. Professor YANG Wei made diagnosis and treatment according to the relationship between different types of anorectal diseases and the five zang- organs. For example，when treating constipation，attention is paid to the role of lung in diffusing and dispersing，and medicinals for diffusing the lung and ventilating are often added. When treating functional anorectal pain， the treatment is to soothe the liver and nourish the heart，and regulate conception and governor vessels， and Gangtong Prescription is self-prescribed. For patients with organic anorectal diseases with anxiety and sadness， the treatment starts from the liver， and additionally applies medicinals for calming the mind， soothing the liver and resolving constraint based on syndrome differentiation. For patients with ulcerative colitis，regardless of whether they have constipation and diarrhea，attention are paid to the ascending and descending functions of the spleen and stomach. For patients with inflammatory bowel disease，habitual constipation and other chronic diseases， the treatment often starts from the kidney treatment， and attention is paid to generating the origin and consolidating the root as well as supplementing both the spleen and the kidney.