Abstract： Objective： To observe the effect of point pressing with essential oil on postoperative pain and comfort in patients with chronic sinusitis and nasal polyps after nasal endoscopic surgery. Methods：A total of 120 patients with chronic sinusitis and nasal polyps after nasal endoscopic surgery under general anesthesia were selected and divided into the control group and the observation group according to the convenient sampling method， with 60 cases in each group. The control group received routine postoperative care，and the observation group received point pressing with essential oil based on routine postoperative care. The changes in scores of Visual Analogue Scale (VAS)，General Comfort Questionnaire (GCQ)， and Pittsburgh Sleep Quality Index (PSQI) were compared between the two groups at different postoperative time periods. Results：The VAS scores in the observation group at 6 hours，24 hours，and 48 hours after surgery were lower than those in the control group，differences being significant (P＜0.05). After surgery， the GCQ scores in the two groups were decreased when compared with those before surgery，and the GCQ score in the observation group was higher than that in the control group，differences being significant (P＜0.05). After surgery， the PSQI scores in the two groups were increased when compared with those before surgery，and the PSQI score in the observation group was lower than that in the control group，differences being significant (P＜0.05). During treatment，neither group experienced any significant adverse reactions. Conclusion： For patients with chronic sinusitis and nasal polyps after nasal endoscopic surgery，point pressing with essential oil can alleviate the pain level，improve comfort level， and improve sleep quality.