Abstract： Objective： To observe the clinical effect of Jiangzhuo Mixture for asymptomatic hyperuricemia of internal obstruction of turbid phlegm type. Methods：A total of 64 cases of patients with hyperuricemia of internal obstruction of turbid phlegm type without obvious gout symptoms were randomly divided into the treatment group and the control group according to the random number table method，with 32 cases in each group. Both groups were given lifestyle intervention；the control group was given the oral administration of Benzbromarone Tablets，and the treatment group was additionally treated with Jiangzhuo Mixture based on the treatment of the control group. Both groups were treated for 4 weeks. The clinical effects were compared between the two groups；the blood uric acid levels，traditional Chinese medicine (TCM) syndrome scores and adverse reactions were compared before and after treatment between the two groups. Results：The total effective rate was 90.63% in the treatment group，higher than that of 71.88% in the control group (P＜0.05). After treatment， the levels of serum uric acid in the groups were decreased (P＜0.05)， and the level in the treatment group was lower than that in the control group (P＜0.05). After treatment，the TCM syndrome scores of thirst without a desire to drink and heavy head in the control group were decreased (P＜0.05)；the TCM syndrome scores of thirst without a desire to drink，fatigue，lack of strength，sloppy stool，and heavy head in the treatment group were decreased (P＜0.05)，and the above TCM syndrome scores in the treatment group were lower than those in the control group (P＜0.05). There was no significant difference being found in the comparison of the incidence of adverse reactions between the two groups (P＞0.05). Conclusion：The combination of Benbrommarone Tablets with Jiangzhuo Mixture for asymptomatic hyperuricemia of interal obstruction of turbid phlegm syndrome type can significantly improve the levels of serum uric acid，reduce the rate of uric acid recovery，and effectively improve the clinical symptoms of internal obstruction of turbid phlegm.