Study on Differences of Relevant Indexes in Patients with G5D Stage of Chronic Kidney Disease with Different Traditional Chinese Medicine Syndrome Types Who Underwent Maintenance Hemodialysis with Parathyroidectomy
Abstract: Objective: To observe the differences of general data and laboratory indexes in patients with G5D stage of chronic kidney disease (CKD) with different traditional Chinese medicine(TCM) syndrome types who underwent maintenance hemodialysis (MHD) and parathyroidectomy (PTX). Methods: The general data of patients with different TCM syndorme types were collected, including gender, age, dialysis duration,primary affection,age of starting dialysis,interval between intact parathyroid hormone (iPTH) elevation and PTX, and the laboratory indexes, including hemoglobin (Hb), iPTH, blood calcium (Ca) and blood phosphorus (P). Results: Comparing the age and age of starting dialysis of patients with different TCM syndrome types showed significance in the differences (P<0.05). Specifically,the patients with syndrome of kidney yang depletion were older than those with syndrome of spleen yang deficiency and syndrome of accumulated damp-heat,patients with liver-kidney yin deficiency syndrome were older than those with syndrome of accumulated damp- heat, and patients with syndrome of kidney yang depletion and liver-kidney yin deficiency syndrome firstly received dialysis at an older age than those with syndrome of accumulated damp- heat, differences being significant (P<0.05). There was no significant difference being found in the overall comparisons of gender, interval among iPTH and PTX treatment and dialysis duration among patients with different TCM syndrome types (P>0.05). There was no significant difference being found in the comparisons of proportions of hypertension,glomerular nephropathy,renal anemia and other basic diseases among patients with different TCM syndrome types (P>0.05). Before surgery, the comparisons of levels of Hb and iPTH among patients with different TCM syndrome types (P<0.05). The Hb levels of patients with syndrome of accumulated damp- heat were lower than those of patients with syndrome of spleen yang deficiency,and the iPTH levels of patients with syndrome of accumulated dampheat and syndrome of kidney yang depletion were higher than those of patients with syndrome of spleen yang deficiency and liver- kidney yin deficiency syndrome, differences being significant (P<0.05). There was no significant difference being found in the overall comparisons of levels of blood P and blood Ca among patients with different TCM syndrome types (P>0.05). One month after surgery,the overall comparison of Hb level among patients with different TCM syndrome types showed significance in the difference (P< 0.05). The Hb levels of patients with syndrome of accumulated damp- heat were lower than those of patients with syndrome of spleen yang deficiency, differences being significant (P<0.05). There was no significant difference being found in the overall comparisons of levels of blood P,blood Ca and iPTH among patients with different TCM syndrome types (P>0.05). Conclusion: The main TCM syndrome type of patients after receiving MHD and PTX is the syndrome of spleen yang deficiency. There were significant differences in the age, age of starting dialysis, levels of Hb and iPTH of patients with different TCM syndrome types one month before and after surgery.