Abstract： Objective： To observe the clinical effect of point application combined with Zopiclone for insomnia complicated with hypertension and its effect on sleep quality. Methods： A total of 68 patients with insomnia and hypertension were randomly divided into the control group and the observation group， with 34 cases in each group. The control group received routine antihypertensive and Zopiclone therapy， and the observation group additionally received point application therapy based on the treatment of the control group. Both groups were treated for 1 month. Traditional Chinese medicine (TCM) syndrome scores，Pittsburgh Sleep Quality Index (PSQI) scores，systolic blood pressure (SBP)，and diastolic blood pressure (DBP) levels before and after treatment， as well as the clinical effects were observed and compared between the two groups. Results： The total effective rate was 94.12% in the observation group，and 76.47% in the control group，the difference being significant (P＜0.05). After treatment，the scores of TCM syndromes such as restlessness at night， prolonged inability to sleep， dizziness and distending pain， bloating and irritability in the two groups were decreased when compared with those before treatment (P＜0.05)，and the scores in the observation group were lower than those in the control group (P＜0.05). After treatment， the scores of sleep quality， time to fall asleep， sleep time， sleep efficiency， insomnia symptoms， daytime dysfunction， and use of sleep aids of PSQI in the two groups were decreased when compared with those before treatment (P＜0.05)，and the scores in the observation group were lower than those in the control group (P＜0.05). After treatment，the levels of SBP and DBP in the two groups were decreased when compared with those before treatment (P＜0.05)，and the levels of SBP and DBP in the observation group were lower than those in the control group (P＜0.05). Conclusion： The combination of point application therapy and Zopiclone for insomnia complicated with hypertension can improve clinical effects，and further improve blood pressure levels，sleep quality，and TCM syndromes.