Abstract：With the change of the times，the incidence of obesity and its complications has gradually increased， resulting in a huge social， economic and medical burden. Professor LI Huilin holds that the accumulation of pathogen in phlegm，dampness，stasis，heat，cold，qi constraint，and food is the main factor leading to obesity， and obesity can foster pathogen in turn； struggle between the healthy qi and pathogenic qi ultimately forms the deficiency syndrome，leading to various diseases. Therefore，Professor LI proposes for the first time that “obesity is the primary factor of all diseases” and uses the three methods of sweat promotion， dispersion， and purgation to dispel pathogen for the first step. Once the pathogen is expelled，the healthy qi can be preserved.