Abstract： To introduce the clinical experience of Chief Physician JI Bing in treating obese impaired glucose tolerance by syndrome differentiation from yin fire. JI Bing believes that the basis of yin fire is spleen-stomach qi deficiency and that the water，grain and essence cannot be transformed and generated may lead to either the constraint of turbid pathogen or dampness blocking the lower，which further causes various changes and even the internal heat；the obese impaired glucose tolerance belongs to the splenic pure heat in Chinese medicine， and its nature is spleen- stomach weakness. The basic pathogenesis of splenic pure heat is latent heat in the deficiency of middle energizer. Therefore， the treatment of obese impaired glucose tolerance by syndrome differentiation from yin fire should regulate and nourish the spleen and stomach and enrich and nourish the original qi. In other words，that is to boost the original qi，promote clear yang and drain yin fire.