加味枳术汤联合埋线及生物反馈治疗盆底失弛缓型便秘临床研究
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574.62

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浙江省台州市社会发展科技计划项目(XM20210046)


Clinical Study on Modified Zhizhu Decoction Combined with Catgut Embedment and Biofeedback for Unrelaxed Pelvic Floor Syndrome-Induced Constipation
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    摘要:

    目的:观察加味枳术汤联合埋线及生物反馈治疗盆底失弛缓型便秘(UPFS) 的临床效果。方法: 选取80 例气虚型UPFS 患者,按随机数字表法分为对照组和观察组各40 例。对照组给予单纯生物反馈治疗仪 训练治疗,观察组在对照组基础上给予加味枳术汤联合埋线治疗。2 组均以10 d 为1 个疗程,治疗3 个疗程。 评价2 组临床疗效,比较2 组治疗前后便秘临床症状评分、肛门直肠压力和盆底肌电信号水平,观察不良反应 发生情况。结果:观察组总有效率为95.00%,高于对照组80.00%,差异有统计学意义(P<0.05)。治疗后, 2 组排便时间、排便间隔、排便费力感、肛门坠胀感、排便不尽感评分及总积分较治疗前降低(P<0.05),且 观察组排便时间、排便间隔、排便费力感、肛门坠胀感、排便不尽感评分及总积分均低于对照组(P<0.05)。 治疗后,2 组肛管静息压、最大收缩压、排便感觉阈值较治疗前下降,最大耐受量较治疗前升高(P<0.05); 且观察组肛管静息压、最大收缩压、排便感觉阈值低于对照组,最大耐受量高于对照组(P<0.05)。治疗后, 2 组盆底肌电活力值、最大峰值、功值较治疗前升高(P<0.05),且观察组盆底肌电活力值、最大峰值、功值 水平高于对照组(P<0.05)。2 组不良反应发生率比较,差异无统计学意义(P>0.05)。结论:加味枳术汤联 合埋线及生物反馈治疗气虚型UPFS 患者疗效显著,能改善其便秘症状和肛门直肠压力,提高患者盆底表面肌 电水平,安全性好。

    Abstract:

    Abstract: Objective: To observe the clinical effect of the therapy of Modified Zhizhu Decoction combined with catgut embedment and biofeedback on unrelaxed pelvic floor syndrome (UPFS)- induced constipation. Methods: A total of 80 UPFS- induced constipation patients of qi deficiency type were selected and divided into the control group and the observation group according to the random number table method , with 40 patients in each group. The control group was simply given biofeedback training for treatment,and the observation group was additionally treated with Modified Zhizhu Decoction combined with catgut embedment based on the treatment of the control group. With 10 days as a course of treatment, the two groups were treated for 2 tourses. The clinical effects in the two groups were evaluated;clinical symptom scores of constipation,anorectal pressure and pelvic floor electromyography levels were compared before and after treatment between the two groups,and the occurrence of adverse reactions was observed. Results: The total effective rate was 95.00% in the observation group, higher than that of 80.00% in the control group,the difference being significant (P<0.05). After treatment,the scores of defecation time,defecation interval,defecation effort,anal distension and persistent sensation of defecation and the total scores in the two groups were decreased when compared with those before treatment (P<0.05), and the above symptom scores and the total score in the observation group were lower than those in the control group (P<0.05). After treatment, the anal canal resting pressure, maximum systolic pressure and threshold of defecation sensation in the two groups were decreased when compared with those before treatment,and the maximum tolerance was increased when compared with that before treatment (P<0.05);the anal canal resting pressure,maximum systolic pressure and threshold of defecation sensation in the observation group were lower than those in the control group, and the maximum tolerance in the observation group was higher than that in the control group (P<0.05). After treatment,the vitality value,maximum peak value and work value of pelvic floor electromyography in the two groups were increased when compared with those before treatment (P<0.05),and the above values in the observation group were higher than those in the control group (P<0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P>0.05). Conclusion: The therapy of Modified Zhizhu Decoction combined with catgut embedment and biofeedback has a significant effect on the treatment of UPFS- induced constipation patients of qi deficiency type, which can improve the symptoms of constipation and anorectal pressure, and enhance the levels of pelvic floor surface electromyography,with good safety.

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扈小健,李易蓉.加味枳术汤联合埋线及生物反馈治疗盆底失弛缓型便秘临床研究[J].新中医,2023,55(17):62-66

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  • 在线发布日期: 2023-09-07
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