Abstract：Objective：To observe the effect of modified swallowing mouth muscle training exercises on swallowing function and quality of life in patients with acute exacerbation of chronic obstructive pulmonary disease (COPD). Methods：A total of 56 cases of COPD patients with classification more than Grade II in water swallow test were selected and divided into the control group and the observation group according to the random number table method， with 28 cases in each group respectively. During the study, 3 cases dropped off in the two groups, finally 25 cases were included in the study in each group. The control group was treated with swallowing electrical stimulation therapy， and the observation group was additionally treated with modified swallowing mouth muscle training exercises based on the treatment of the control group. Both groups were treated for 10 days. The scores of Chronic Obstructive Pulmonary Disease Assessment Test Questionnaire (CAT) and water swallow test classification were compared between the two groups. Results： After treatment， the scores of cough， sputum volume， chest discomfort， panting，labour being affected，outgoing activities limitations，sleep，vigor，and the total scores in the two groups were decreased when compared with those before treatment，and each score and total score in CAT in the observation group were lower than those in the control group，differences being significant (P＜0.05). The score of water swallow test in the observation group was decreased when compared with that before treatment， and lower than that in the control group， differences being significant (P＜0.05). There was no significant difference being found in the comparison of scores of water swallow test in the control group before and after treatment (P＞0.05). Conclusion： Modified swallowing mouth muscle training exercises can improve swallowing function and quality of life in patients with acute exacerbation of COPD.