Abstract：Objective：To observe the clinical effect of Huoxue Ningxin Anshen Prescription combined with point application for stable angina pectoris (SAP) of coronary heart disease complicated with insomnia. Methods： A total of 96 cases of patients with SAP complicated with insomnia were divided into the observation group and the control group according to the random number table method，with 48 cases in each group. Both groups were given routine western medicine treatment of SAP； the control group was additionally treated with the oral administration with Estazolam，and the observation group was additionally treated with Huoxue Ningxin Anshen Prescription combined with point application based on the treatment of the control group. After a four- week treatment，the curative effect of angina pectoris and insomnia，the incidence of angina pectoris were compared between the two groups；traditional Chinese medicine (TCM) syndrome scores and Pittsburgh sleep quality index (PSQI) scores were compared between the two groups before and after treatment. Results： The total effective rate of angina pectoris was 86.58% in the observation group and 72.92% in the control group， the difference being significant (P＜0.05). The total effective rate of insomnia was 95.83% in the observation group and 81.25% in the control group， the difference being significant (P＜0.05). Before treatment，there was no significant difference being found in the comparison of the frequency and duration of angina pectoris between the two groups (P＞0.05). After treatment， the frequency and duration of angina pectoris in the two groups were decreased when compared with those before treatment (P＜0.05)，and the two indexes in the observation group were less than those in the control group (P＜0.05). Before treatment，there was no significant difference being found in the comparison of TCM syndrome scores and PSQI scores between the two groups (P＞0.05). After treatment， TCM syndrome scores and PSQI scores in the two groups were decreased when compared with those before treatment (P＜0.05)，and the two scores in the observation group were lower than those in the control group (P＜0.05). Conclusion： In the adjuvant therapy of SAP complicated with insomnia， Huoxue Ningxin Anshen Prescription combined with point application can effectively relieve the symptoms of angina pectoris and insomnia，improve TCM syndrome scores，and enhance clinical effects.