Abstract： Objective： To observe the effect of low- frequency therapeutic instrument of the ebb and flow of midnight and midday for swallowing disorders after cerebral infarction. Methods：A total of 92 cases of patients with swallowing disorders after cerebral infarction were divided into two groups，with 46 cases in each group. Both groups were treated with three- level prevention and treatment of cerebral infarction and swallowing function training，and the observation group was additionally treated with low- frequency therapeutic instrument of the ebb and flow of midnight and midday. Both groups were treated for 21 days. The clinical effects were compared between the two groups. The Water Swallow Test (WST)， Videofluoroscopic Swallowing Study (VFSS) and surface electromyography (sEMG) were conducted before and after treatment. The scores of Standardized Swallowing Assessment (SSA) and Swallowing Quality-of- Life (SWAL-QOL) questionnaire were evaluated. Results：After treatment，the total clinical effective rate was 89.1% in the observation group and 71.7% in the control group，the difference being significant (P＜ 0.05). The WST grading results in the two groups were better than those before treatment (P＜0.05)，and the WST grading result in the observation group was better than that in the control group (P＜0.05). The SSA scores in the two groups were decreased when compared with those before treatment (P＜0.05)， the scores of VFSS and SWAL- QOL were increased when compared with those before treatment (P＜0.05). The SSA score in the observation group was lower than that in the control group (P＜0.05)，and the scores of VFSS and SWAL- QOL were higher than those in the control group (P＜0.05). The maximum wave amplitude of sEMG in the two groups were increased when compared with those before treatment (P＜ 0.05)， and the swallowing time were shortened when compared with those before treatment (P＜0.05)； the maximum wave amplitude of sEMG in the observation group was higher than that in the control group (P＜0.05)， and the swallowing time was shorter than that in the control group (P＜0.05). Conclusion： Based on three-level prevention and treatment of cerebral infarction and swallowing function training，the additional application of low-frequency therapeutic instrument of the ebb and flow of midnight and midday for swallowing disorders after acute cerebral infarction can enhance curative effect，and effectively improve swallowing function and quality of life.