清热化痰宣肺合剂联合西药治疗痰热壅肺型社区获得性肺炎临床研究
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R563.1

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宁夏回族自治区重点研发项目(2020BEG03065);银川市学术技术带头人储备工程项目(银人才发〔2021〕5号)


Clinical Study on Qingfei Huatan Xuanfei Mixture Combined with Western Medicine for Community-Acquired Pneumonia of Phlegm-Heat Obstructing the Lung Type
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    摘要:

    目的:观察清热化痰宣肺合剂联合西药治疗痰热壅肺型社区获得性肺炎的临床疗效。方法:采用 随机数字表法将80 例社区获得性肺炎患者分为对照组、治疗组各40 例。对照组给予常规西药治疗,治疗组在 对照组基础上加用清热化痰宣肺合剂治疗。比较2 组治疗前后中医证候积分、白细胞计数、中性粒细胞百分 比,比较2 组证候疗效总有效率、胸部CT 炎症吸收总有效率及安全性。结果:治疗后,治疗组证候疗效总有 效率92.50%,高于对照组85.00% (P<0.05)。治疗组胸部CT 炎症吸收总有效率77.50%,高于对照组 55.00%(P<0.05)。治疗后,2 组中医证候积分(主症积分、次症积分、总分)、白细胞计数、中性粒细胞百 分比均较治疗前降低(P<0.05),且治疗组治疗后中医证候积分、白细胞计数均低于对照组(P<0.05)。2 组 均未出现严重不良反应。结论:清热化痰宣肺合剂联合西药治疗痰热壅肺型社区获得性肺炎疗效确切,能够促 进患者肺部炎症吸收,减少感染,安全性较高。

    Abstract:

    Abstract:Objective:To observe the clinical effect of Qingfei Huatan Xuanfei Mixture combined with western medicine for community-acquired pneumonia of phlegm-heat obstructing the lung type. Methods: A total of 80 cases of patients with community-acquired pneumonia were divided into the control group and the treatment group according to the random number table method, with 40 cases in each group. The control group was treated with routine western medicine,and the treatment group was additionally treated with Qingfei Huatan Xuanfei Mixture based on the treatment of the control group. Traditional Chinese medicine (TCM) syndrome scores,white blood cell count and neutrophil percentage were compared before and after treatment between the two groups;the total effective rate of curative effect of syndromes,the total effective rate of chest CT inflammation absorption,and the safety in the two groups were compared. Results: After treatment, the total effective rate of curative effect of syndromes was 92.50% in the treatment group,higher than that of 85.00% in the control group (P<0.05). The total effective rate of chest CT inflammation absorption was 77.50% in the treatment group,higher than that of 55.00% in the control group (P<0.05). After treatment, TCM syndrome scores (main symptom score, secondary symptom score, the total score), white blood cell counts and neutrophil percentage in the two groups were decreased when compared with those before treatment (P<0.05),and TCM syndrome score,white blood cell count in the treatment group were lower than those in the control group (P<0.05). No serious adverse reaction was observed in the two groups. Conclusion: Qingfei Huatan Xuanfei Mixture combined with western medicine has a definite curative effect in the treatment of community- acquired pneumonia of phlegm-heat obstructing the lung type,which can promote the absorption of lung inflammation and reduce infection,with high safety.

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雷小宁,乔路敏,李晶.清热化痰宣肺合剂联合西药治疗痰热壅肺型社区获得性肺炎临床研究[J].新中医,2023,55(11):95-98

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  • 在线发布日期: 2023-06-16
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