凝露散冰剂联合西药治疗低温等离子射频消融术后临床研究
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R766.18

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Clinical Study on Coagulation of Herbal Decoction Combined with Western Medicine for Patients After Low-Temperature Plasma Radiofrequency Ablation
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    摘要:

    目的:观察凝露散冰剂联合西药治疗低温等离子射频消融术后的临床疗效及对咽部恢复的影响。 方法:采用随机数字表法将300 例拟行低温等离子射频消融术治疗的扁桃体炎手术患者分为对照组及试验组各 150 例。2 组均进行低温等离子射频消融术治疗,对照组术后采用常规西药治疗,试验组在对照组基础上联用 凝露散冰剂治疗。比较2 组术后黏膜消肿、伪膜脱落及正常饮食时间;比较2 组治疗前后视觉模拟评分 法(VAS) 评分、中医证候积分及白细胞介素-6(IL-6)、肿瘤坏死因子-α(TNF-α) 水平;比较2 组临床疗 效及不良反应发生率。结果:试验组总有效率高于对照组(P<0.05),术后黏膜消肿时间、伪膜脱落时间及正 常饮食时间均短于对照组(P<0.05)。2 组治疗后中医证候积分、IL-6、TNF-α 水平均低于治疗前(P< 0.05),且试验组治疗后中医证候积分及IL-6、TNF-α 水平低于对照组(P<0.05)。治疗1 d、3 d、5 d 后, 2 组VSA 评分均较治疗前降低(P<0.05),且试验组治疗3 d、5 d 后VAS 评分低于对照组(P<0.05)。试验 组不良反应发生率低于对照组(P<0.05)。结论:凝露散冰剂联合西药治疗低温等离子射频消融术后疗效确 切,能够有效减轻术后患者疼痛症状,降低炎症因子,加快创面愈合时间,安全性较高。

    Abstract:

    Abstract: Objective: To observe the clinical effect of coagulation of herbal decoction combined with western medicine for patients after low- temperature plasma radiofrequency ablation and its effects on pharyngeal recovery. Methods:A total of 300 cases of patients with tonsillitis who were to be treated by low- temperature plasma radiofrequency ablation were divided into the control group and the trial group according to the random number table method,with 150 cases in each group. Both groups were treated with low-temperature plasma radiofrequency ablation;the control group was treated with routine western medicine after the surgery,and the trial group was additionally treated with coagulation of herbal decoction based on the treatment of the control group. The time of mucosa detumescence, pseudomenbrane detachment,and the recovery of normal diet after the surgery were compared between the two groups. The scores of Visual Analogue Scale (VAS),traditional Chinese medicine (TCM) syndrome scores,and the levels of interleukin- 6 (IL- 6) and tumor necrosis factor- α (TNF- α) were compared before and after treatment between the two groups. Clinical effects and the incidence of adverse reactions were compared between the two groups. Results: The total effective rate in the trial group was higher than that in the control group (P<0.05),and the time of mucosa detumescence,pseudomenbrane detachment,and the recovery of normal diet after the surgery in the trial group were shorter than those in the control group (P< 0.05). After treatment,TCM syndrome scores and the levels of IL- 6 and TNF- α in the two groups were lower than those in the control group (P<0.05),and the TCM syndrome scores and the levels of IL-6 and TNF-α in the trial group were lower than those in the control group (P<0.05). The VAS scores after 1,3, and 5 days of treatment in the two groups were decreased when compared with those before treatment (P<0.05),and the VAS scores after 3,and 5 days of treatment respectively in the trial group were lower than those in the control group (P<0.05). The incidence of adverse reactions in the trial group was lower than that in the control group (P<0.05). Conclusion: coagulation of herbal decoction combined with western medicine has a definite curative effect for patients after low- temperature plasma radiofrequency ablation,and effectively relieve postoperative pain,reduce inflammatory factors,and shorten the time of wound healing,with high safety.

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郭丽,韩云飞.凝露散冰剂联合西药治疗低温等离子射频消融术后临床研究[J].新中医,2023,55(9):103-107

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  • 在线发布日期: 2023-05-24
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