Abstract： Objective： To observe the curative effect of Shexiang Baoxin Pills combined with Torasemide on chronic congestive heart failure (CHF) and its effects on vascular endothelial function. Methods： A total of 103 patients with CHF were given retrospective analysis and divided into the control group and the treatment group according to different treatment methods， with 51 and 52 cases in each group. The control group was treated with the intravenous injection of Torasemide， and the treatment group was additionally given Shexiang Baoxin Pills based on the treatment of the control group. Before and after treatment， the changes of scores of main symptoms， indexes of heart function， including left ventricular ejection fraction (LVEF)， stroke volume (SV) and cardiac index (CI)， indexes of vascular endothelial function， including endothelin (ET)， nitric oxide (NO) and brachial artery flow- mediated dilatation (FMD) as well as levels of B- type natriuretic peptide (BNP) were compared between the two groups. The clinical effects and incidence of adverse reactions in both groups were also analyzed. Results： The total effective rate was 94.23% in the treatment group， and 80.39% in the control group， the difference being significant(P＜0.05). Before treatment，there was no significant difference being found in the comparisons of scores of palpitation，shortness of breath，fatigue and lack of strength，facial edema and bloated limbs， and chest distress (pain) between the two groups (P＞0.05)； after treatment， the above five scores in both groups were decreased when compared with those before treatment (P＜0.05)， and the above five scores in the treatment group were lower than those in the control group (P＜0.05). Before treatment， there was no significant difference being found in the comparisons of levels of LVEF， SV and CI between the two groups (P＞0.05)；after treatment，the above three levels of indexes of heart function in the two groups were increased when compared with those before treatment (P＜0.05)，and the above three levels in the treatment group were higher than those in the control group (P＜0.05). Before treatment，there was no significant difference being found in the comparisons of levels of ET，NO，FMD and BNP between the two groups (P＞0.05). After treatment，the levels of ET and BMP in the two groups were decreased when compared with those before treatment (P＜0.05)， and the levels of NO and FMD were increased when compared with those before treatment (P＜0.05)； the improvement in above four indexes in the treatment group was more significant than that in the control group (P＜0.05). During treatment，the incidence of adverse reactions was 7.69% in the treatment group，and 9.80% in the control group， there being no significance in the difference between the two groups (P＞0.05). Conclusion： Shexiang Baoxin Pills combined with Torasemide has a significant clinical effect on patients with CHF， which can effectively improve the symptoms of heart failure，the heart function and the vascular endothelial function of patients，and reduce the BNP level，with good safety.