Abstract：Objective：To observe the effect of acupuncture combined with manipulation on pain relief of temporomandibular joint disorders and functional recovery of jaw joint. Methods：A total of 86 cases of patients with temporomandibular joint disorders were divided into the observation group and the control group according to the random number table method，with 43 cases in each group. The control group was treated with acupuncture， and the observation group was treated with acupuncture combined with manipulation. Both groups were treated for 4 weeks. The changes in pain scores， clicking of joint， maximum mouth opening，and temporomandibular joint function were compared between the two groups. The clinical effects and treatment safety in the two groups were evaluated. Results：The total effective rate was 93.02% in the observation group， higher than that of 79.07% in the control group (P＜0.05). After treatment，Visual Analogue Scale (VAS) scores and clicking of joint in the two groups were decreased when compared with those before treatment，and the maximum mouth opening was increased when compared with that before treatment (P＜0.05)； the VAS scores and clicking of joint in the observation group were lower than those in the control group，and the maximum mouth opening was higher than that in the control group (P＜0.05). After treatment， mandibular movement， joint noise， pressure palpation of joint， and dysfunction index (DI) in the two groups were decreased when compared with those before treatment (P＜ 0.05)； mandibular movement， joint noise， pressure palpation of joint， and DI in the observation group were lower than those in the control group (P＜0.05). Conclusion：Acupuncture combined with manipulation can improve the symptoms of pain， clicking of joint and mouth opening limitation in patients with temporomandibular joint disorders，promote the functional recovery of temporomandibular joint，improve the clinical effect，and have high safety.