参芪扶正注射液对宫颈癌术后化疗患者症状、免疫功能的影响
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R737.33

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Effect of Shenqi Fuzheng Injection on Symptom and Immune Function of Patients Undergoing Chemotherapy After Surgery for Cervical Cancer
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    摘要:

    目的:观察参芪扶正注射液对宫颈癌术后化疗患者症状、免疫功能的影响。方法:选择88 例接受 宫颈癌手术治疗的患者,以随机数字表法分为治疗组与对照组各44 例。2 组术后均采取常规化疗方案治疗, 治疗组在化疗期间给予参芪扶正注射液治疗,2 组均治疗8 周。比较2 组临床疗效、不良反应发生率,以及治 疗前后中医证候积分、免疫功能指标。结果:治疗后,治疗组临床疗效总有效率84.09%,高于对照组 65.91% (P<0.05)。治疗后,2 组中医证候积分均较治疗前降低(P<0.05),治疗组中医证候积分低于对照 组(P<0.05)。治疗后,2 组辅助性T 细胞(Th) 水平、Th/抑制性T 细胞(Ts) 值均较治疗前降低(P< 0.05),对照组Th 水平、Th/Ts 值比治疗组降低更明显(P<0.05);2 组Ts 水平均较治疗前升高(P<0.05), 对照组Ts 水平比治疗组升高更明显(P<0.05)。治疗组不良反应发生率25.00%,低于对照组45.45% (P< 0.05)。结论:参芪扶正注射液治疗宫颈癌术后化疗患者,可改善其临床症状,提高机体免疫功能,减少化疗 引起的不良反应。

    Abstract:

    Abstract: Objective: To observe the effect of Shenqi Fuzheng Injection on symptom and immune function of patients undergoing chemotherapy after surgery for cervical cancer. Methods : A total of 88 cases of patients receiving surgery for cervical cancer were selected and divided into the treatment group and the control group according to the random number table method,with 44 cases in each group. Both groups were treated with routine chemotherapy after surgery,and the treatment group was treated with Shenqi Fuzheng Injection during chemotherapy. Both groups were treated for 8 weeks. Traditional Chinese medicine (TCM) syndrome scores and immune function indexes before and after treatment as well as clinical effects and incidence of adverse reactions were compared between the two groups. Results: After treatment,the total effective rate of clinical effect was 84.09% in the treatment group,higher than that of 65.91% in the control group (P<0.05). After treatment, the TCM syndrome scores in the two groups were decreased when compared with those before treatment (P<0.05), and the TCM syndrome score in the treatment group was lower than that in the control group (P<0.05). After treatment,the levels of helper T cell (Th) and Th/suppressor T cell (Ts) values in the two groups were decreased when compared with those before treatment (P<0.05), and the levels of Th and Th/Ts value in the control group were significantly lower than those in the treatment group (P<0.05); the levels of Ts in the two groups were increased when compared with those before treatment (P<0.05),and the levels of Ts in the control group was significantly higher than that in the treatment group (P<0.05). The incidence of adverse reactions was 25.00% in the treatment group, lower than that of 45.45% in the control group (P<0.05). Conclusion: Shenqi Fuzheng Injection for patients undergoing chemotherapy after surgery for cervical cancer can improve their clinical symptoms, enhance immune function and reduce adverse reactions caused by chemotherapy.

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周珏伊,冯继红,赵丽萍,虞伟妃.参芪扶正注射液对宫颈癌术后化疗患者症状、免疫功能的影响[J].新中医,2023,55(6):136-139

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  • 在线发布日期: 2023-03-28
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