Abstract： Objective： To observe the curative effect of refined moxibustion therapy for cervical insomnia and its effect on blood flow resistance index in carotid artery. Methods： A total of 52 cases of patients with cervical insomnia were selected and divided into the control group and the treatment group according to the random number table method，with 26 cases in each group. The control group was treated with estazolam，and the treatment group was additionally treated with refined moxibustion therapy based on the treatment of the control group. Both groups were treated for four weeks. After treatment， the clinical effects in the two groups were evaluated. Before and after treatment， the levels of blood flow resistance index(RI) in internal carotid artery and vertebral artery in the two groups were compared. Before and after treatment，and one month after treatment，the scores of Pittsburgh Sleep Quality Index(PSQI) in the two groups were compared. Results：The total effective rate was 88.46% in the treatment group and 65.38% in the control group， the difference being significant(P＜0.05). Before treatment， there was no significant difference being found in the comparison of PSQI scores between the two groups(P＞0.05). After treatment and one month after the end of treatment，the PSQI scores of the two groups were lower than those before treatment，and the PSQI scores of the treatment group were lower than those of the control group at the same time point，the difference being significant(P＜0.05). Before treatment，there was no significant difference being found in the comparison of RI in internal carotid artery and vertebral artery between the two groups(P＞0.05). After treatment，the RI of internal carotid artery and vertebral artery in the two groups were lower than that before treatment，and the two indexes in the treatment group were lower than those in the control group， the difference being significant(P＜0.05). Conclusion： Estazolam combined with refined moxibustion therapy has a significant curative effect in treating cervical insomnia， which can effectively improve RI in internal carotid artery and vertebral artery and sleep quality.