Clinical Study on Modified Jiannao Chuchan Tang Combined with Levodopa Bensera⁃ zide Tablets for Parkinson Disease with Stirring Wind due to Yin Deficiency Syndrome
Abstract:Objective:To observe the clinical effect of modified Jiannao Chuchan Tang combined with levodopa benserazide tablets for Parkinson disease with stirring wind due to yin deficiency syndrome. Methods: A total of 82 cases of patients with Parkinson disease with stirring wind due to yin deficiency syndrome were divided into the control group and the observation group according to the random number table method, with 41 cases in each group. The control group was treated with Levodopa Benserazide Tablets,and the observation group was additionally treated with modified Jiannao Chuchan Tang based on the treatment of the control group. Both groups were treated for three months. The scores of traditional Chinese medicine(TCM) syndromes and Unified Parkinson Disease Rating Scale(UPDRS) as well as the clinical effects in the two groups were compared,and the adverse reactions were observed. Results:After treatment, the scores of primary and secondary symptoms in the two groups were decreased when compared with those before treatment(P<0.05), and the above scores in the observation group were lower than those in the control group(P<0.05). After treatment, the scores of UPDRS in the two groups were decreased when compared with those before treatment(P<0.05), and the score of UPDRS in the observation group was lower than that in the control group(P<0.05). The total effective rate was 97.56% in the observation group, higher than that of 75.61% in the control group(P<0.05). There was one case of nausea and vomiting in the observation group and six cases in the control group,all of which were caused by taking medicine on an empty stomach,and the symptoms disappeared after avoiding taking medicine on an empty stomach. Conclusion:The therapy of modified Jiannao Chuchan Tang combined with Levodopa Benserazide Tablets is safe and effective in the treatment of Parkinson disease with stirring wind due to yin deficiency syndrome.