Abstract：Objective：To observe the clinical effect of the therapy of Buzhong Yiqi Tang combined with moxibustion at points along channels based on the theory of "abnormal ascent-descent between clear yang and turbid yin". Methods：A total of 92 patients with functional constipation were retrospectively studied and divided into the control group and the study group according to different treatment methods，with 40 and 52 cases in each group. The control group was treated with conventional western medicine，and the study group was treated with Buzhong Yiqi Tang combined with moxibustion. After 14 days of treatment， the clinical effects and recurrence， and the scores of constipation symptoms， traditional Chinese medicine (TCM) syndrome scores and the first defecation time before and after treatment were compared between the two groups. Results：The total clinical effective rate was 96.15% in the study group and 75.00% in the control group， the difference being significant(P＜0.05). Before treatment， there was no significant difference in the scores of major symptoms such as defecation interval， defecation duration， defecation difficulty and defecation intention between the two groups(P＞0.05). After treatment， the scores of the above symptoms were decreased when compared with those before treatment(P＜0.05)， and the above scores in the study group were lower than those in the control group(P＜0.05). Before treatment， there was no significant difference in TCM syndrome scores of sweating and shortness of breath， abdominal distention，fatigue after defecation，bowel sounds and flatus，pale face and mental fatigue(P＞0.05). After treatment，the scores of the above TCM syndromes in both groups were decreased when compared with those before treatment(P＜0.05)， and the above scores in the study group were lower than those in the control group(P＜0.05). After treatment，the first defecation time in the study group was shorter than that in the control group，the difference being significant(P＜0.05). The recurrence rate was 10.42% in the study group and 40.00% in the control group， the intergroup comparison showed that the difference being significant(P＜0.05). Conclusion： Based on the theory of "abnormal ascent- descent between clear yang and turbid yin"，the application of Buzhong Yiqi Tang combined with moxibustion at points along channels in the treatment of functional constipation can effectively improve the clinical effect， improve the patient's defecation state，and reduce the recurrence rate.