解毒养阴清肺汤联合康复训练对早期肺癌术后患者肺功能和免疫功能的影响
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R734.2

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Effect of Jiedu Yangyin Qingfei Tang Combined with Rehabilitation Training on Lung Function and Immune Function in Patients for Post-surgery of Early Lung Cancer
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    摘要:

    目的:观察解毒养阴清肺汤联合康复训练对早期肺癌术后患者肺功能和免疫功能的影响。方法:选取90 例肺癌早期术后患者,按随机数字表法分为观察组和对照组各45 例。对照组采用康复训练,观察组在对照组基础上联合解毒养阴清肺汤口服。评价2 组临床疗效,比较2 组治疗前后肺功能、免疫功能及生活质量。结果:观察组总有效率为95.56%,高于对照组77.78% (P<0.05)。术后8 周,2 组每分钟最大通气量(MVV)、第1 秒用力呼气容积(FEV1)、用力肺活量(FVC) 较术前下降(P<0.05),但观察组下降程度小于对照组(P<0.05)。术后8 周,对照组CD3+、CD4+、CD4+/CD8+较术前下降(P<0.05);观察组CD3+、CD4+较术前增高(P<0.05),且观察组CD3+、CD4+高于对照组(P<0.05)。术后8 周,2 组生活质量各维度评分较术前增高(P<0.05),观察组增高程度高于对照组(P<0.05)。结论:解毒养阴清肺汤联合康复训练治疗早期肺癌术后患者的疗效较好,可改善患者肺功能,提高免疫功能和生活质量。

    Abstract:

    Abstract: Objective: To observe the effect of the therapy of Jiedu Yangyin Qingfei Tang combined with rehabilitation training on lung function and immune function in patients for post- surgery of early lung cancer. Methods:A total of 90 patients after surgery for early lung cancer were assigned to the observation group and the control group according to the random number table method,with 45 cases in each group. The control group was treated with rehabilitation training, and the observation group was additionally treated with Jiedu Yangyin Qingfei Tang orally based on the treatment of the control group. The clinical effects in the two groups were evaluated. Before and after treatment,the lung function,immune function and quality of life were compared between the two groups. Results:The total effective rate was 95.56% in the observation group, higher than that of 77.78% in the control group(P<0.05). Eight weeks after surgery,the maximum minute ventilation(MMV),forced expiratory volume in one second(FEV1) and forced vital capacity(FVC) in the two groups were decreased when compared with those before(P<0.05),and the decrease in the observation group was less than that in the control group(P<0.05). Eight weeks after surgery,the levels of CD3 +,CD4 + and CD4 +/CD8 + in the control group were decreased when compared with those before surgery(P<0.05),the levels of CD3+ and CD4+ in the observation group were increased, and the level of CD3+ and CD4+ in the observation group were better than than in the control group(P<0.05). Eight weeks after surgery,each score of quality of life in the two groups was increased when compared with that before pre- surgery(P<0.05),and the increase in the observation group was higher than that in the control group(P<0.05). Conclusion: The therapy of Jiedu Yangyin Qingfei Tang combined with rehabilitation training has a good curative effect on patients for post- surgery of early lung cancer,which can improve the lung function and enhance the immune function and quality of life.

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蔡群慧,周雯,丁传彪,徐斌.解毒养阴清肺汤联合康复训练对早期肺癌术后患者肺功能和免疫功能的影响[J].新中医,2022,54(21):156-159

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  • 在线发布日期: 2022-11-15
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