Abstract：Objective：To observe the effect of hot medicated compress with Quhan Chushi Prescription combined with occipito-mandibular traction for cervical spondylotic radiculopathy with wind-cold-dampness syndrome. Methods： A total of 104 cases of patients with cervical spondylotic radiculopathy with windcold- dampness syndrome were divided into the control group and the observation group according to the random number table method，with 52 cases in each group. The control group was treated with occipitomandibular traction， and the observation group was treated with hot medicated compress with Quhan Chushi Prescription combined with occipito-mandibular traction. The clinical effects in the two groups were compared. Before and after treatment，Chinese medicine syndrome scores，the scores of Visual Analogue Scale(VAS) and Clinical Assessment Scale for Cervical Spondylosis(CASCS)，and cervical range of motion in the two groups were compared. Results： The total recovery rate was 98.08% in the observation group， higher than that of 86.54% in the control group(P＜0.05). After treatment，the scores of various traditional Chinese medicine(TCM) syndromes including pain in neck，shoulder and limbs，numbness in upper limbs， stiffness in neck， heaviness in upper limbs and activity limitation as well as the total scores in the two groups were decreased when compared with those before treatment(P＜0.05)；the scores of various TCM syndromes and the total score in the observation group were lower than those in the control group(P＜0.05). After treatment，the scores of VAS in the two groups were decreased when compared with those before treatment(P＜0.05)， and the scores of CASCS were increased(P＜0.05)； the scores of VAS in the observation group was lower than those in the control group(P＜0.05)，and the scores of CASCS was higher (P＜0.05). After treatment，the degrees of cervical flexion，cervical lateral flexion，cervical extension and cervical rotation in the two groups were increased when compared with those before treatment(P＜0.05)； the degrees of cervical flexion， cervical lateral flexion， cervical extension and cervical rotation in the observation group were higher than those in the control group(P＜0.05). Conclusion： The therapy of hot medicated compress with Quhan Chushi Prescription combined with occipito- mandibular traction for patients with cervical spondylotic radiculopathy with wind- cold- dampness syndrome can significantly relieve their clinical symptoms， alleviate their pain， restore the normal structure and function of cervical spine，and improve the recovery rate.