Abstract：Objective：To study the administration rule of Prof. PAN Junhui in differentiating and treating lung cancer based on the Chinese Medicine Inheritance Auxiliary Platform，so as to provide reference for designing the treatment of lung cancer by "treating lung cancer from the neutral in Lingnan area". Methods： The medical records of Prof. PAN in treating lung cancer in the outpatient department from May 2019 to April 2021 were collected， screened according to the inclusion criteria and exclusion criteria， and then entered into the Chinese Medicine Inheritance Auxiliary Platform V2.5 to establish a database and conduct systematic analysis. The medication frequency was counted；Apriori algorithm and association rules were used to analyze and extract the core combination of prescriptions(support set as 0.45，confidence as 0.8)； complex system cluster analysis was used to mine the internal core herbal combination and new prescription combination(correlation set as 12，penalty as 7). Results：A total of 163 medical records were included，with a total of 796 prescriptions involving 150 kinds of Chinese herbs. The top 10 most frequently used herbs were Radix et Rhizoma Rhodiolae Crenulatae， Placenta Hominis， Radix et Rhizoma Glycyrrhizae Praeparata cum Melle，acetous Rhizoma Curcumae，Pericarpium Trichosanthis，Bulbus Allii Macrostemi， Rhizoma Pinelliae Praeparatum， Herba Epimedii， Radix Astragali and Rhizoma Atractylodis Macrocephalae. The top 10 high- frequency herbal combinations in core herbal combinations from high to low were Radix et Rhizoma Glycyrrhizae Praeparata cum Melle- Placenta Hominis， Radix et Rhizoma Glycyrrhizae Praeparata cum Melle- Radix et Rhizoma Rhodiolae Crenulatae， Pericarpium Trichosanthis- Placenta Hominis，Pericarpium Trichosanthis-Bulbus Allii Macrostemi，Pericarpium Trichosanthis-Radix et Rhizoma Rhodiolae Crenulatae， Rhizoma Pinelliae Praeparatum- Radix et Rhizoma Rhodiolae Crenulatae， Placenta Hominis- Bulbus Allii Macrostemi， Placenta Hominis- Radix et Rhizoma Rhodiolae Crenulatae， Placenta Hominis- acetous Rhizoma Curcumae， Bulbus Allii Macrostemi- Radix et Rhizoma Rhodiolae Crenulatae； among them， Radix et Rhizoma Rhodiolae Crenulatae， Placenta Hominis， Pericarpium Trichosanthis， Bulbus Allii Macrostemi， acetous Rhizoma Curcumae， Radix et Rhizoma Glycyrrhizae Praeparata cum Melle， and Rhizoma Pinelliae Praeparatum appeared many times in multiple herbal combinations， which were the core of the associated network. A total of 10 potential new prescriptions were obtained， including Semen Coicis- Rhizoma Phragmitis- Semen Persicae- Cortex Lycii- Semen Benincasae， mature Radix Codonopsis- Bulbus Allii Macrostemi- Guangdong Rhizoma Cimicifugaenorthern Radix Bupleuri-Rhizoma Pinelliae Praeparatum-Pericarpium Trichosanthis，Radix Paeoniae Alba- Radix Rehmanniae Praeparata-Radix et Rhizoma Asteris-Semen Persicae-Flos Carthami-vinous Rhizoma Chuanxiong. Conclusion： Prof. PAN's clinical syndrome differentiation and treatment of lung cancer is based on the principle of reinforcing healthy qi and dispelling pathogenic factors. He takes warming the kidney and clearing the lung as the fundamental treatment，supplemented by dissolving stasis，softening hard masses and dissipating masses，invigorating blood，fortifying the spleen and supplementing qi，and dispelling wind，unblocking the collaterals and dissolving phlegm.