Abstract：Objective：To observe the clinical effect of modified Lishui Ruangan tang for cirrhotic ascites with qi stagnation and blood stasis syndrome. Methods： A total of 78 cases of patients with cirrhotic ascites with qi stagnation and blood stasis syndrome were selected for retrospective study and were divided into the observation group and the control group according to different treatment measures，with 39 cases in each group. The control group was given routine symptomatic treatment，and the observation group was additionally treated with modified Lishui Ruangan tang based on the treatment of the control group. Both groups were treated for three courses， with four weeks being one course. The changes in abdominal circumference and 24- hour urine volume before and after treatment， as well as clinical effects were compared between the two groups. Results：The total effective rate was 97.4% in the observation group and 76.9% in the control group，the difference being significant(P＜0.05). Before treatment，there was no significant difference being found in the comparison of abdominal circumference between the two groups (P＞0.05). After treatment， levels of abdominal circumference in the two groups were decreased when compared with those before treatment(P＜0.05)；there were few differences in abdominal circumference between the two groups(P＞0.05)， but the difference of abdominal circumference before and after treatment in the treatment group was larger than that in the control group， and the difference was statistically significant(P＜0.05). Before treatment， there was no significant difference being found in the comparison of 24- hour urine volumes between the two groups(P＞0.05). After treatment，24- hour urine volumes in the two groups were significantly decreased when compared with those before treatment(P＜ 0.05)，and the 24-hour urine volume and the difference before and after treatment in the observation group were larger than those in the control group(P＜0.05). The incidence of adverse reactions was 5.1% in the observation group and 10.3% in the control group，there being no significance in the difference(P＞0.05). Conclusion：Modified Lishui Ruangan tang for cirrhotic ascites with qi stagnation and blood stasis syndrome has a reliable clinical effect， which can effectively improve 24- hour urine volume and abdominal circumference with relatively few adverse reactions.