Abstract: Objective: To observe the clinical effect of modified Huangqi Chifeng tang combined with Duhuo Jisheng tang for ischemic stroke in convalescence. Methods:A total of 102 cases of patients with ischemic stroke in convalescence were divided into the combination group and the control group according to the random number table method, with 51 cases in each group. The control group was treated with routine western medicine, and the combination group was treated with modified Huangqi Chifeng tang combined with Duhuo Jisheng tang and routine western medicine. The clinical effects in the two groups were compared. Before and after treatment,Chinese medicine syndrome scores,tumor necrosis factor-α (TNF-α),interleukin-6(IL-6),high-sensitivity C-reactive protein(hs-CRP),whole blood viscosity at high shear rate, whole blood viscosity at low shear rate, blood plasma viscosity, simplified Fugl- Meyer Assessment(FMA) and Activities of Daily Living Scale(ADL) scores in the two groups were compared. Results:The total clinical effective rate was 92.16% in the combination group,higher than that of 70.59% in the control group(P<0.05). After treatment, the Chinese medicine syndrome scores, the levels of TNF- α, IL- 6 and hs- CRP, the whole blood viscosity at high shear rate, whole blood viscosity at low shear rate, and blood plasma viscosity in the two groups were decreased when compared with those before treatment(P<0.05), and the scores of FMA and ADL were increased(P<0.05); the Chinese medicine syndrome scores, the levels of TNF- α, IL-6 and hs-CRP,the whole blood viscosity at high shear rate,whole blood viscosity at low shear rate,and blood plasma viscosity in the combination group were lower than those in the control group(P<0.05), and the scores of FMA and ADL were higher(P< 0.05). Conclusion: Modified Huangqi Chifeng tang combined with Duhuo Jisheng tang for patients with ischemic stroke in convalescence can effectively improve the clinical effect and hemorheology indexes , relieve clinical symptoms and reduce levels of TNF- α, IL-6 and hs-CRP in serum,which is of great significance to improve limb motor function and self-care ability of patients.